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Prof. Dr. Sepp D. Kohlwein

Karl-Franzens-Universität Graz, Institut für Molekulare Biowissenschaften, BioTechMed-Graz

© S.D. Kohlwein / Foto Furgler, Graz

Prof. Dr. Sepp D. Kohlwein

Sepp D. Kohlwein, born in 1954, studied Technical Chemistry at Graz University of Technology and received his technical doctorate there in 1982 at the Institute of Biochemistry. Until 2001, he worked there as an associate professor. After several research stays at the Albert Einstein College of Medicine, Bronx, NY as well as at the Carnegie Mellon University, Pittsburgh, PA, he qualified as a docent in 1992 for the subject of biochemistry at the Graz University of Technology. In 2001, Sepp Kohlwein was appointed to the Institute of Molecular Biosciences at the University of Graz, where he heads the research group Yeast Genetics and Molecular Biology.

Leitmotif

“Basic research is indispensable for gaining new insights and it is an essential tool for training critical, problem-oriented thinking.”

Activities

Kohlwein is the author of more than 160 publications (https://www.ncbi.nlm.nih.gov/pubmed/?term=kohlwein) and has been involved as project leader and vice-speaker (*) in numerous national and international research networks over the past three decades, for example NFN “Yeast Molecular Biology”, the EU projects Elife (European Lipidomics Initiative) and EUROFEN (Yeast Functional Analysis Network), the special research areas (biocatalysis, biomembranes*, Lipotox) as well as the Austrian genome research program GEN-AU (Project GOLD*) and the PhD program “Molecular Enzymology”. He is the initiator of the Bioimaging Graz Platform and co-director of the Nikon Center for Excellence in Superresolution Microscopy: Cells and Organells.

Awards

In 1985 he was awarded the Schrödinger Fellowship of the Austrian Science Fund FWF. In 2010 he received the Research Award of the Austrian province of Styria for his research on the important role of fats in cell growth and cell division.

Focus

His scientific research interests include the lipid metabolism in yeast as a model for metabolic diseases as well as the implementation of novel imaging techniques for studying the membrane and organelle structure and their dynamics in yeast.

Methods

  • Yeast molecular biology, including high throughput methods to identify and analyze genetic interactions
  • High-end Microscopy, Confocal Laser Scanning Microscopes, Multi-Photon Microscopy (SHG, CARS), STORM Super Resolution Microscopy
  • Lipidomics, lipid mass spectroscopy

Facts, background information, dossiers

  • metabolic diseases
  • lipid metabolism
  • lipidomics
  • cell growth
  • superresolution microscopy
  • fats

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