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Tracking Inline Cell Count and Dimension to Ensure Targeted Cell Culture Productivity

This online seminar will introduce tools used in fermentation and outline a number of academic and industrial case studies on fermentation processes including E. Coli, mammalian cells, plant cells and filamentous organisms. Inline Process Analytical Technology (PAT) has become critical to ensuring productivity in the biotechnology industry. Return on investment in Process Analytical Technology (PAT) comes from R&D and manufacturing. Typically, this is achieved by getting more robust processes to market quicker which ultimately minimizes the process risks from batch to batch and also improves process optimization. With the advent of in-process Process Analytical Technology (PAT) tools for particle/cell characterization one can quantify particle/cell number and dimension in applications such as fermentation, separation, and formulation. Application examples include: Ensure cell culture productivity by detecting the mode of cell death (apoptosis) through changes in cell number and dimension Monitor cell count, cell density in real time with no need for sampling Study cell debris and cell debris flocculation Streamline scale-up from shaker flasks to the pilot scale Optimized protein crystallization.

Type of Event: On-Demand Webinars
By appointment: Yes
Language: English
  • process analytical technology
  • fermentation
  • separation
  • protein crystallization
  • process optimization
  • mammalian cells
  • flocculation
  • cells
  • cell density
  • cell death
  • biotechnology
  • apoptosis

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q&more – the networking platform for quality excellence in lab and process

The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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