Webinar Part II: Environment and Sampling Instrument environment focuses on maintaining the instrument environment within an operable temperature range. Guidance is presented accounting for the instrument installation location (inside or in external conditions) and the corresponding tempera ... more
Online Monitoring of MicroEncapsulation
The main factors that affect the microencapsulation procedure and final microparticles are: Matrix material level, composition, and inherent viscosity Physiochemical properties of the active ingredient being entrapped Matrix/active ingredient ration Nature of the solvent employed Level and properties of the stabilizer used Shearing stress and the temperature of the emulsification A MicroEmulsion example from the US Food and Drug Administration (FDA) is used during the presentation to show how to: Understand the droplet system's response when changing process parameters. Optimize the process by choosing conditions which ensure consistent endpoints, batch repeatability and process stability. Scale-up the particle distribution while avoiding batch failure or inconsistency process performance and product quality.
|Type of Event:||On-Demand Webinars|