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13 Current news about the topic amino acids

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Sweet lysine degradation

Glucogenic lysine degradation found for the first time

03-Dec-2018

In fact, they were looking for a specific enzyme. What they found is something so fundamental that their new findings might well find their way into textbooks. Referred to here is the amino acid lysine, which is an important building block in proteins. In bacteria and many other organisms, lysine ...

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Genetic disease healed using genome editing

10-Oct-2018

A team of researchers from ETH Zurich and the University Children’s Hospital Zurich applied a newly developed editing tool to target and correct genetic mutations. By doing so, the researchers healed mice suffering from a genetic metabolic disorder that also affects humans. Parents of newborns ...

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A natural product that could lead to new class of commercial herbicide and drugs

The weed killer could potentially be used to find new drugs for antibacterial medicines.

17-Jul-2018

A garden can be a competitive environment. Plants and unseen microorganisms in the soil all need precious space to grow. And to gain that space, a microbe might produce and use chemicals that kill its plant competitors. But the microbe also needs immunity from its own poisons. By looking for that ...

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New technology for enzyme design

05-Jun-2018

Scientists at the University of Würzburg have chemically modified the enzyme levansucrase using a new method. The enzyme can now produce sugar polymers that are exciting for applications in the food industry and medicine. Enzymes are tools of nature that accelerate almost all biochemical ...

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Potential 'missing link' in chemistry that led to life on earth found

08-Nov-2017

Chemists at The Scripps Research Institute (TSRI) have found a compound that may have been a crucial factor in the origins of life on Earth. Origins-of-life researchers have hypothesized that a chemical reaction called phosphorylation may have been crucial for the assembly of three key ...

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Neutrons observe vitamin B6-dependent enzyme activity useful for drug development

18-Oct-2017

Scientists at the Department of Energy's Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria and ...

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A new ligand extends the half-life of peptide drugs from minutes to days

18-Jul-2017

Peptides are biological molecules, made up of short sequences of amino acids. Because they are easy to synthesize, show low toxicity and high efficiency, peptides such as insulin and other hormones can be used as drugs. But peptides are quickly cleared by the kidneys, which means that we can only ...

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New technology offers fast peptide synthesis

02-Mar-2017

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections. To help speed up the manufacturing process, MIT researchers have designed a machine that can rapidly ...

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Bacterium from coal mine fire could aid drug targeting

08-Feb-2017

Chemists scouring Appalachia for exotic microorganisms that could yield blockbuster drugs have reported a unique find from the smoldering remains of a coal mine fire that's burned for nearly a decade in southeastern Kentucky. In new findings a research team from Rice University, the University of ...

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Rapid synthesis towards optically active alpha-aminocarbonyl therapeutics

New catalytic asymmetric reaction directly installs amines into carbonyl compounds

24-Nov-2016

A team of organic chemists at ITbM, Nagoya University, has developed a new reaction to directly install amines into carbonyl compounds using their unique phase-transfer catalyst. This unprecedented method leads to the rapid formation of optically active (chiral) α-aminocarbonyls, which are ...

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