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22 Current news about the topic biochemistry

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Opening the cavity floodgates

Biochemists investigate the transport of large proteins through bacterial cell membranes

25-Jan-2018

Every cell is surrounded by a membrane, which ensures the internal biochemical milieu and regulates the exchange of substances with its surroundings. In every cell membrane, there are a large number of transporters that allow only one sort of molecule to pass through. In the case of very small ...

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Less chewing the cud, more greening the fuel

09-Jan-2018

Plant biomass contains considerable calorific value but most of it makes up robust cell walls, an unappetising evolutionary advantage that helped grasses to survive foragers and prosper for more than 60 million years. The trouble is that this robustness still makes them less digestible in the ...

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Identifying the right target

Protein structure could unlock new treatments for cystic fibrosis

15-Dec-2017

Biochemists at the University of Zurich have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of effective drugs to treat cystic fibrosis. Cystic fibrosis is a severe hereditary disease of ...

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Protein-folding simulations sped up

08-Dec-2017

Proteins, the ubiquitous workhorses of biochemistry, are huge molecules whose function depends on how they fold into intricate structures. To understand how these molecules work, researchers use computer modeling to calculate how proteins fold. Now, a new algorithm can accelerate those vital ...

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New TB drugs possible with understanding of old antibiotic

07-Dec-2017

Tuberculosis, and other life-threatening microbial diseases, could be more effectively tackled with future drugs, thanks to new research into an old antibiotic by the University of Warwick and The Francis Crick Institute. Led by Professor David Roper at Warwick's School of Life Sciences and Dr ...

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Researchers fold a protein within a protein

15-Nov-2017

A team from the NUS Yong Loo Lin School of Medicine (NUS Medicine) has invented a fundamentally new way of folding and protecting recombinant proteins. Sourced from the rapidly expanding field of synthetic biology, this protein-in-a-protein technology can improve functional protein yields by ...

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Potential 'missing link' in chemistry that led to life on earth found

08-Nov-2017

Chemists at The Scripps Research Institute (TSRI) have found a compound that may have been a crucial factor in the origins of life on Earth. Origins-of-life researchers have hypothesized that a chemical reaction called phosphorylation may have been crucial for the assembly of three key ...

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Cool microscope technology revolutionises biochemistry

04-Oct-2017

We may soon have detailed images of life’s complex machineries in atomic resolution. The Nobel Prize in Chemistry 2017 is awarded to Jacques Dubochet, Joachim Frank and Richard Henderson for the development of cryo-electron microscopy, which both simplifies and improves the imaging of ...

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An unusual delivery service

01-Sep-2017

Is it better to produce locally or to import? That can be a crucial question for simple lifeforms as well. Mitochondria, the power plants of the cell, have their own protein factories although the cell apparatus could easily do the job for them. A special species of eukaryotes even has all the ...

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Expanding the reach of therapeutic antibodies

31-Aug-2017

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy. Antibodies are proteins produced by the immune system that specialize in recognizing ...

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