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25 Current news about the topic biochemistry

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Supercomputer simulations show new target in HIV-1 replication

14-Aug-2018

HIV-1 replicates in ninja-like ways. The virus slips through the membrane of vital white blood cells. Inside, HIV-1 copies its genes and scavenges parts to build a protective bubble for its copies. Scientists don't understand many of the details of how HIV-1 can fool our immune system cells so ...

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A natural product that could lead to new class of commercial herbicide and drugs

The weed killer could potentially be used to find new drugs for antibacterial medicines.

17-Jul-2018

A garden can be a competitive environment. Plants and unseen microorganisms in the soil all need precious space to grow. And to gain that space, a microbe might produce and use chemicals that kill its plant competitors. But the microbe also needs immunity from its own poisons. By looking for that ...

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New type of photosynthesis discovered

18-Jun-2018

The discovery changes our understanding of the basic mechanism of photosynthesis and should rewrite the textbooks. It will also tailor the way we hunt for alien life and provide insights into how we could engineer more efficient crops that take advantage of longer wavelengths of light. The ...

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Opening the cavity floodgates

Biochemists investigate the transport of large proteins through bacterial cell membranes

25-Jan-2018

Every cell is surrounded by a membrane, which ensures the internal biochemical milieu and regulates the exchange of substances with its surroundings. In every cell membrane, there are a large number of transporters that allow only one sort of molecule to pass through. In the case of very small ...

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Less chewing the cud, more greening the fuel

09-Jan-2018

Plant biomass contains considerable calorific value but most of it makes up robust cell walls, an unappetising evolutionary advantage that helped grasses to survive foragers and prosper for more than 60 million years. The trouble is that this robustness still makes them less digestible in the ...

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Identifying the right target

Protein structure could unlock new treatments for cystic fibrosis

15-Dec-2017

Biochemists at the University of Zurich have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of effective drugs to treat cystic fibrosis. Cystic fibrosis is a severe hereditary disease of ...

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Protein-folding simulations sped up

08-Dec-2017

Proteins, the ubiquitous workhorses of biochemistry, are huge molecules whose function depends on how they fold into intricate structures. To understand how these molecules work, researchers use computer modeling to calculate how proteins fold. Now, a new algorithm can accelerate those vital ...

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New TB drugs possible with understanding of old antibiotic

07-Dec-2017

Tuberculosis, and other life-threatening microbial diseases, could be more effectively tackled with future drugs, thanks to new research into an old antibiotic by the University of Warwick and The Francis Crick Institute. Led by Professor David Roper at Warwick's School of Life Sciences and Dr ...

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Researchers fold a protein within a protein

15-Nov-2017

A team from the NUS Yong Loo Lin School of Medicine (NUS Medicine) has invented a fundamentally new way of folding and protecting recombinant proteins. Sourced from the rapidly expanding field of synthetic biology, this protein-in-a-protein technology can improve functional protein yields by ...

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Potential 'missing link' in chemistry that led to life on earth found

08-Nov-2017

Chemists at The Scripps Research Institute (TSRI) have found a compound that may have been a crucial factor in the origins of life on Earth. Origins-of-life researchers have hypothesized that a chemical reaction called phosphorylation may have been crucial for the assembly of three key ...

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