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7 Current news about the topic crispr

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A Pair of RNA Scissors with Many Functions

Arming CRISPR/Cas systems with an enzyme that also controls the translation of genetic information into protein

08-Feb-2018

CRISPR/Cas systems are known as promising “gene scissors” in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA – and perhaps they can even be used to correct genetic defects. A team of scientists led by Juliane Behler and Prof. Dr. Wolfgang Hess ...

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Multifunctional platform for the delivery of gene therapeutics

Thermo-triggered release of a genome-editing machinery by modified gold nanoparticles

24-Jan-2018

Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the “gene scissors” to the tumor cell genome. As the authors report, their nonviral transport and release platform of gene-editing ...

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Searching for the CRISPR Swiss-army knife

13-Dec-2017

Scientists at the University of Copenhagen, led by the Spanish Professor Guillermo Montoya, are investigating the molecular features of different molecular scissors of the CRISPR-Cas system to shed light on the so-called 'Swiss-army knives' of genome editing. Montoya's research group has ...

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Making mosquitoes self-destruct

16-Nov-2017

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA. As proof of ...

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CRISPR gene editing can cause hundreds of unintended mutations

31-May-2017

As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome. "We feel it's critical that the scientific community consider the potential hazards of all ...

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Testing the Efficacy of New Gene Therapies More Efficiently

22-Mar-2017

Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested more rapidly and more cost-effectively in the lab for their efficacy. A team of researchers from the University of Zurich and the Children’s Hospital ...

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Automating DNA origami opens door to many new uses

31-May-2016

Researchers can build complex, nanometer-scale structures of almost any shape and form, using strands of DNA. But these particles must be designed by hand, in a complex and laborious process. This has limited the technique, known as DNA origami, to just a small group of experts in the field. Now ...

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