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38 Current news about the topic dna

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Speed limit on DNA-making sets pace for life's first steps

15-Mar-2019

Fruit flies make for stingy mothers, imparting only a portion of the genetic building blocks their offspring need to survive. The rest must be produced by the fertilized egg in its first few steps of growth. Scientists puzzled for two decades over this seemingly unnecessary withholding. Now ...

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Going fishing in the protein pond using histones as a bait – how do cells decide how to repair their DNA?

27-Feb-2019

When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum München made major contributions, elucidates the molecular basis by which a cell makes the choice ...

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Structure of virus that infects bacteria in hot springs is revealed

06-Feb-2019

Scientists have revealed the structure of a virus infecting bacteria that thrive in 160-degree hot springs in places like Yellowstone National Park in Wyoming. The discovery could lead to better targeted delivery of drugs into cells and new DNA sequencing technology, according to a study by ...

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It's all in the code

Protein production efficiency can be predicted by gene sequence

06-Feb-2019

Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact quantities of all proteins produced and degraded by a given cell in various experimental ...

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Carrying and releasing nanoscale cargo with 'nanowrappers'

Nanocubes for biomedicine, catalysis and beyond

08-Jan-2019

This holiday season, scientists at the Center for Functional Nanomaterials (CFN)--a U.S. Department of Energy Office of Science User Facility at Brookhaven National Laboratory--have wrapped a box of a different kind. Using a one-step chemical synthesis method, they engineered hollow metallic ...

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Mutant protein tackles DNA guardian to promote cancer development

How tumour development is driven by mutations in important gene in preventing cancer

09-Nov-2018

Melbourne scientists have discovered how tumour development is driven by mutations in the most important gene in preventing cancer, p53. The research revealed that in the early stages of cancer, mutant p53 'tackles' the normal p53 protein and blocks it from carrying out its protective role. As a ...

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Repeated interferon stimulation creates innate immune memory

29-Oct-2018

The innate immune system may be able to be trained to react to viral infections more efficiently by repeated exposure to anti-viral signaling molecules. Mammalian cells seem to be able to memorize anti-viral stimulation at the level of DNA-packaging molecules, enabling faster and greater ...

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Pathogens may evade immune response with metal-free enzyme required for DNA replication

23-Oct-2018

Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions. This process may allow infectious bacteria to replicate even when the host's immune system sequesters iron ...

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Nanocages in the lab and in the computer

How DNA-based dendrimers transport nanoparticles

22-Oct-2018

How to create nanocages, i.e., robust and stable objects with regular voids and tunable properties? Short segments of DNA molecules are perfect candidates for the controllable design of novel complex structures. Physicists from the University of Vienna, the Technical University of Vienna, the ...

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Liver-on-a-chip, the ideal test environment for CRISPR

16-Oct-2018

Two Arizona State University professors are among the first recipients ofSomatic Cell Genome Editing (SCGE) grants from the National Institutes of Health Common Fund. The $2,600,000, five-year grant will fund the first study of the genome editing technology CRISPR to be used on a "human liver ...

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