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27 Current news about the topic dna

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Precise, Highly Efficient Gene Repair

Researchers develop new CRISPR/Cas process using Japanese ricefish

31-Aug-2018

The molecular tool CRISPR/Cas allows introducing DNA double strand breaks into any gene of interest consequently resulting in stochastic mutations at the site of the target gene. However, precise gene repair through the application of a rescue construct suffers from limited efficiency. ...

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Marking breast implants with tomato DNA to prevent counterfeiting

02-Aug-2018

For years, a French company sold breast implants made of cheap industrial silicone components. Headline news when it broke in 2010, this scandal is still keeping the courts busy today. Now, a research team at the Fraunhofer Institute for Applied Polymer Research IAP has come up with a method to ...

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Less failure in CRIPSR gene editing

Biochemists discover cause of genome editing failures

13-Jul-2018

Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient. CRISPR is a gene-editing tool that allows scientists to cut out unwanted genes or genetic material from DNA, ...

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The world's tiniest first responders

'Walking molecules' haul away damaged DNA to the cell's emergency room

22-Jun-2018

The cell has its own paramedic team and emergency room to aid and repair damaged DNA, a new USC Dornsife study reveals. The findings are timely, as scientists are delving into the potential of genome editing with the DNA-cutting enzyme, CRISPR-Cas9, to treat diseases or to advance scientific ...

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Stone age hepatitis B virus decoded

Viral DNA shows the hepatitis B virus has been circulating in Europe for at least 7.000 years

14-May-2018

An international team of scientists led by researchers at Kiel University in the scope the CRC 1266 “Scales of Transformation” and the Max Planck Institute for the Science of Human History has successfully reconstructed genomes from Stone Age and Medieval European strains of the hepatitis B ...

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Understanding how DNA is selectively tagged with 'do not use' marks

09-May-2018

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times. One way that cells keep these genetic elements under ...

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Tiny nanomachine successfully completes test drive

11-Apr-2018

Together with colleagues from the USA, scientists from the University of Bonn and the research institute Caesar in Bonn have used nanostructures to construct a tiny machine that constitutes a rotatory motor and can move in a specific direction. The researchers used circular structures from ...

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DNA mimic outwits viral enzyme

Biomimetic chemistry

04-Apr-2018

Not only can synthetic molecules mimic the structures of their biological models, they can also take on their functions and may even successfully compete with them, as an artificial DNA sequence designed by LMU chemist Ivan Huc now shows. Chemist Ivan Huc finds the inspiration for his work in the ...

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Newly discovered CRISPR mechanism may help prevent dangerous errors

Better understanding of how gene editing works may make process safer

02-Mar-2018

Even as CRISPR gene-editing technology is offering insights into genetic diseases, researchers are discovering new things about how it actually works. In the first of two papers just published in the Journal of the American Chemical Society (JACS), researchers at The Ohio State University report ...

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A protein that self-replicates

01-Mar-2018

Long regarded as a biological aberration, amyloids are fibrous aggregates of short protein fragments. Amyloids have a bad reputation because they are thought to be the cause of multiple neurodegenerative diseases, including Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. It was only ...

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