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17 Current news about the topic rna

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Understanding how DNA is selectively tagged with 'do not use' marks

09-May-2018

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times. One way that cells keep these genetic elements under ...

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Who am I? How cells find their identity

02-May-2018

The research group of Alex Schier, Director of the Biozentrum, University of Basel, has investigated more closely how a single embryonic cell develops into a heart, nerve or blood cell. For the first time, the researchers have been able to reconstruct the developmental trajectories of individual ...

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Scientists characterise cancer genes using ground-breaking new method

09-Apr-2018

In a paper in the journal “Science”, researchers from the Vienna BioCenter combine cutting-edge technologies to decipher regulatory functions of important cancer genes. Key to this success is an innovative method called “SLAMseq”, which allows the direct detection of sudden changes in gene ...

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A protein that self-replicates

01-Mar-2018

Long regarded as a biological aberration, amyloids are fibrous aggregates of short protein fragments. Amyloids have a bad reputation because they are thought to be the cause of multiple neurodegenerative diseases, including Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. It was only ...

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A Pair of RNA Scissors with Many Functions

Arming CRISPR/Cas systems with an enzyme that also controls the translation of genetic information into protein

08-Feb-2018

CRISPR/Cas systems are known as promising “gene scissors” in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA – and perhaps they can even be used to correct genetic defects. A team of scientists led by Juliane Behler and Prof. Dr. Wolfgang Hess ...

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Multifunctional platform for the delivery of gene therapeutics

Thermo-triggered release of a genome-editing machinery by modified gold nanoparticles

24-Jan-2018

Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the “gene scissors” to the tumor cell genome. As the authors report, their nonviral transport and release platform of gene-editing ...

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Spaghetti-like, DNA 'noodle origami' the new shape of things to come for nanotechnology

18-Dec-2017

For the past few decades, scientists have been inspired by the blueprint of life, DNA, as the shape of things to come for nanotechnology. This burgeoning field is called DNA origami. Scientist borrowed its moniker from the paper artists who conjure up birds, flowers and planes from imaginatively ...

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Potential 'missing link' in chemistry that led to life on earth found

08-Nov-2017

Chemists at The Scripps Research Institute (TSRI) have found a compound that may have been a crucial factor in the origins of life on Earth. Origins-of-life researchers have hypothesized that a chemical reaction called phosphorylation may have been crucial for the assembly of three key ...

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Circular RNA linked to brain function

16-Aug-2017

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders. While hundreds ...

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Cut the long story short – and stitch it back together

22-Mar-2017

A species of unicellular ciliate has found a special trick to make use of the cellular machinery in seemingly impossible ways. Researchers of the NCCR «RNA & Disease – The Role of RNA Biology in Disease Mechanisms» of the University of Bern have for the first time described a mechanism in detail ...

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