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Genes on sugar

Developing bio-based carrier systems for gene transfer

The targeted transport of DNA and RNA using vectors (mostly made from synthetic polymers) in cell cultures has become part of routine practice in biological R&D – a fact highlighted by the multitude of commercial kits now available. To date, however, obstacles relating to use in patients have ...

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How GxP-regulated laboratories can use digitization as an opportunity

Industry 4.0 concepts that support regulatory compliance and data integrity in lab environments

A few years ago the term “Industry 4.0” was used to describe a future vision of digitized production. This concept is now being implemented by industry. It is characterized by a high degree of automation and networked processes, without which global competitiveness would no longer be achievable.

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Oligomers in polyester-based food packaging

Using mass spectrometry to detect the presence of small polymer molecules

For several decades, food packaging has made handling food easier and helped to maintain its quality. Plastic packaging possesses the advantage that it is light and flexible, with a vast variety of polymer modifications allowing a wide range of usages.

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How prepared are we for the digital transformation in the lab?

Smart and networked solutions pave the way to the laboratory of the future

Laboratory 4.0, the internet of things (IoT), big data, cloud computing or storage, blockchain, cybercrime, thingbots, predictive maintenance, artificial intelligence et al.: the thicket of buzzwords is getting denser almost by the day. They feature in just about every newspaper article about ...

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Key challenges in bioprocessing

Process analytics in biotechnology

As far back in time as several thousand years ago our ancestors were using biotechnical processes to make beer, wine and bread. These days, biotechnological processes are not merely used to produce food – they enable a wide variety of applications, from wastewater treatment to manufacturing ...

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Weighing without touching in a contamination-free working environment

Superconducting levitation enables ultra-clean sterile processes

Like counting objects, measuring their mass belongs to the most elemental characterization processes mankind has performed for thousands of years, from coal bags to sophisticated agents used in the pharma industry, from beam balances to electromagnetic laboratory balances, and from micro to kilo ...

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Highly specific aptamers for analytics and therapeutics

Generating aptamers using an automated in vitro selection method

DNA and RNA aptamers are high-affinity, nucleotide-based binding molecules which, as an alternative to antibodies, are already being widely used in analytics, diagnostics and therapeutics. The generation of new aptamers and their industrial implementation opens up new potentials for a wide range ...

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Vibrational spectroscopy - Label-free imaging

From protein mechanisms to tissue analysis

Spectroscopic methods are now granting us deep insights into biological systems at previously unattainable spatial and temporal resolutions. Complementing the already well-established fluorescence spectroscopy, the major potential of label-free vibrational spectroscopy has become clear in recent ...

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Detect and solve process problems immediately with Jidoka

First-Defect-Stop helps to improve quality through sustainable and reliable processes in weighing

The management concept “Lean Laboratory” is increasingly being implemented in the laboratory environment, with the aim of optimizing efficiency. An essential approach here is the “First-Defect-Stop”, which is based on the Jidoka principle and refers to the earliest possible identification of ...

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Why biosimilars and not biogenerics?

Stringent standards for generic products of highly complex biopharmaceuticals

Medicines produced using genetic techniques have existed since 2006, called “similar biological medicinal products” or “biosimilars”. Until a year ago, this was a fairly low-profile group, even in expert circles. This has all changed now, however, with the recent licensing of the first biosimilar ...

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The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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