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How prepared are we for the digital transformation in the lab?

Smart and networked solutions pave the way to the laboratory of the future

Laboratory 4.0, the internet of things (IoT), big data, cloud computing or storage, blockchain, cybercrime, thingbots, predictive maintenance, artificial intelligence et al.: the thicket of buzzwords is getting denser almost by the day. They feature in just about every newspaper article about ...

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Key challenges in bioprocessing

Process analytics in biotechnology

As far back in time as several thousand years ago our ancestors were using biotechnical processes to make beer, wine and bread. These days, biotechnological processes are not merely used to produce food – they enable a wide variety of applications, from wastewater treatment to manufacturing ...

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Highly specific aptamers for analytics and therapeutics

Generating aptamers using an automated in vitro selection method

DNA and RNA aptamers are high-affinity, nucleotide-based binding molecules which, as an alternative to antibodies, are already being widely used in analytics, diagnostics and therapeutics. The generation of new aptamers and their industrial implementation opens up new potentials for a wide range ...

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Weighing without touching in a contamination-free working environment

Superconducting levitation enables ultra-clean sterile processes

Like counting objects, measuring their mass belongs to the most elemental characterization processes mankind has performed for thousands of years, from coal bags to sophisticated agents used in the pharma industry, from beam balances to electromagnetic laboratory balances, and from micro to kilo ...

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Vibrational spectroscopy - Label-free imaging

From protein mechanisms to tissue analysis

Spectroscopic methods are now granting us deep insights into biological systems at previously unattainable spatial and temporal resolutions. Complementing the already well-established fluorescence spectroscopy, the major potential of label-free vibrational spectroscopy has become clear in recent ...

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Detect and solve process problems immediately with Jidoka

First-Defect-Stop helps to improve quality through sustainable and reliable processes in weighing

The management concept “Lean Laboratory” is increasingly being implemented in the laboratory environment, with the aim of optimizing efficiency. An essential approach here is the “First-Defect-Stop”, which is based on the Jidoka principle and refers to the earliest possible identification of ...

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Why biosimilars and not biogenerics?

Stringent standards for generic products of highly complex biopharmaceuticals

Medicines produced using genetic techniques have existed since 2006, called “similar biological medicinal products” or “biosimilars”. Until a year ago, this was a fairly low-profile group, even in expert circles. This has all changed now, however, with the recent licensing of the first biosimilar ...

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Putting Pressure on Pharmaceuticals

Supercritical fluids as a (literal) solution for formulation platforms

As a general rule, the pharmaceuticals industry develops new drugs by applying a complex procedure of formulation utilising excipients suitable for the final drug dosage form. Such development processes are carried out by the companies’ technical departments and in many cases result in solutions ...

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Analysis in picoliter volumes

Miniaturization of routine lab work with lab-on-a-chip systems

Reducing time, costs and human resources: many basic as well as applied analytical and diagnostic challenges can be performed on lab-on-a-chip systems. They enable sample quantities to be reduced, work steps to be automated and completed in parallel, and are ideal for combination with highly ...

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Workflow

ICH Linearity Studies using Automated Standard Preparation and UHPLC

According to the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), it is necessary to test analytical methods for their linearity as part of a method validation study. The typical process for this is to prepare standards ...

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The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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