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From feast to famine and back – no problem for bacteria

Microorganisms use impressive strategies for dealing with uncertainty

Bacteria are true survivors. In the course of evolution, they have developed numerous strategies to adapt to rapidly changing, uncertain environmental conditions. Their metabolism is much more sophisticated than that of human beings. Within minutes they can regulate their gene expression and, if ...

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Lipidomics – a new kid on the “OMICS” block

An emerging technology to comprehensively describe entire lipid profiles

Progress in research is – to a large extent – driven by technological and analytical advance-ments. This is particularly true for the field of lipid research in the biomedical field, which was hampered for decades by the limited availability of analytical tools to address the enormous complexity ...

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Infrared visualization of sucrose in plants

A novel microspectroscopic method allows sugar mapping across the plant tissue

Quantitative mapping of metabolite distribution has widespread applications in medicine and biology, but has remained a key analytical challenge. A novel method for sugar imag-ing in plants based on the principles of infrared spectroscopy, which was developed at the IPK-Gatersleben, allows the ...

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Biomarkers in nutritional science

Modeling the interaction of dietary ingredients with proteins

Molecular modeling, the modeling of molecular interactions, has become established over the past decades as a standard method in the development of pharmaceuticals. At the Institute for Nutritional Sciences of the University of Potsdam, molecular modeling methods are used in interdisciplinary ...

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Diet, gut microbiota and host lipid metabolism

Multi-omics approach opens up new insights into the microbiome and mammalian lipid synthesis

Nature provides an enormous diversity of lipid molecules that originate from various pathways. Fatty acids are key modules for various lipids, including cell membrane lipids such as phospholipids or triacylglycerols, which are the major components of lipid droplets. Excess lipids or defects in ...

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User interfaces for presenting traceable measurement results

Optimizing the usability of measurement instruments in centralized lab software systems

Easy access and navigation of historical measurement data stored in central laboratory software systems is important to support the documentation and, in particular, the traceability of measurement results. For some instruments it is also useful to grant users access to past measurement data.

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Reduced lead times for added value in the lab

A value stream analysis reveals worthwhile starting points for implementing lean laboratory processes

The process industry is seeing manufacturing structures change, production chains becoming global and higher requirements placed on manufacturing processes. Businesses need to adapt to declining sales volumes and the demand for more specific product characteristics.

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HPLC with non-specific detection in pharmaceutical quality control

Smart sample preparation improves selectivity of analytical procedures for biopharmaceuticals and other drug products

Impurity testing is an essential part of pharmaceutical quality control because toxicity and content of impurities contained in drug products can impair patient safety. This requires suitable, validated analytical methods.

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Extracellular vesicles as biogenic transporters of antibiotics

Development of new drug carriers based on the principles of nature

Developing new antimicrobial treatment strategies is becoming a key challenge in today's medical research. The targeted delivery of drugs into infected human tissue could significantly improve the antibiotic therapies to combat difficult-to-treat microorganisms.

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Light-regulated production of biodegradable plastics

A photoswitchable catalyst system enables tailoring of polymer properties

Light is a powerful tool to manipulate a vast variety of chemical processes. The use of specific photo-chromic molecules allows chemists to perform reactions in a reversible fashion with a high spatio-temporal resolution.

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The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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