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Detect and solve process problems immediately with Jidoka

First-Defect-Stop helps to improve quality through sustainable and reliable processes in weighing

The management concept “Lean Laboratory” is increasingly being implemented in the laboratory environment, with the aim of optimizing efficiency. An essential approach here is the “First-Defect-Stop”, which is based on the Jidoka principle and refers to the earliest possible identification of ...

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Why biosimilars and not biogenerics?

Stringent standards for generic products of highly complex biopharmaceuticals

Medicines produced using genetic techniques have existed since 2006, called “similar biological medicinal products” or “biosimilars”. Until a year ago, this was a fairly low-profile group, even in expert circles. This has all changed now, however, with the recent licensing of the first biosimilar ...

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Vibrational spectroscopy - Label-free imaging

From protein mechanisms to tissue analysis

Spectroscopic methods are now granting us deep insights into biological systems at previously unattainable spatial and temporal resolutions. Complementing the already well-established fluorescence spectroscopy, the major potential of label-free vibrational spectroscopy has become clear in recent ...

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Putting Pressure on Pharmaceuticals

Supercritical fluids as a (literal) solution for formulation platforms

As a general rule, the pharmaceuticals industry develops new drugs by applying a complex procedure of formulation utilising excipients suitable for the final drug dosage form. Such development processes are carried out by the companies’ technical departments and in many cases result in solutions ...

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Analysis in picoliter volumes

Miniaturization of routine lab work with lab-on-a-chip systems

Reducing time, costs and human resources: many basic as well as applied analytical and diagnostic challenges can be performed on lab-on-a-chip systems. They enable sample quantities to be reduced, work steps to be automated and completed in parallel, and are ideal for combination with highly ...

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Accurate weighing results

GWP® (Good Weighing Practice™) Life Cycle Management – 5 steps that support the Lean principles perfectly

A Lean Laboratory focuses on testing products and materials to deliver results in the most efficient way in terms of cost and speed. An accurate result for the customer is a pre-requisite. However, to guarantee accuracy of a weighing device over time requires using the correct balance as well as ...

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Workflow

ICH Linearity Studies using Automated Standard Preparation and UHPLC

According to the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), it is necessary to test analytical methods for their linearity as part of a method validation study. The typical process for this is to prepare standards ...

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Investment for the Future

Quality training pays off

This is a very particular concern and at the same time the demand placed annually on Dr. Irmgard Werner, who, as a lecturer at the ETH Zurich, supports around 65 pharmacy students in the 5th semester practical training in “pharmaceutical analysis”. With joy and enthusiasm for her subject she ...

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The Right Weight*

The new world of automated dosing

Every scientist studying at university was confronted in chemical practicals with the problem of dissolving a given powdered substance in a given solution and producing a solution with the prescribed ­concentration. The first step was to weigh. Armed with a spatula and a small sheet of weighing ...

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Thinking in Models

How do innovations come about?

Whether at home or in the office, our modern lives would be unthinkable without IT and electrical engineering. For industrial manufacturing, the rapid advances made in information and data processing technologies are the drivers of innovation, enabling intelligently controlled, automated ...

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q&more – the networking platform for quality excellence in lab and process

The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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