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Macromolecular environments influence proteins

Studying proteins in the presence of high concentrations of macromolecules (“molecular crowding”) with the aid of confocal fluorescence microscopy

The high-intensity interaction of proteins with other macromolecules can cause signifi cant changes to protein properties such as translational mobility, for example, or their conformational states. Accordingly, the study of proteins in macromolecular environments that typically very closely ...

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Authentic food

Why a single analysis parameter is not enough

Authentic food is growing in popularity with consumers. In a heavily industrialized market, a regional, single-source and/or specially manufactured product is increasingly becoming a guarantor of greater value. In the premium segment in particular, economically motivated “food fraud” can reap ...

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Fitness test of motile cells

Label-free and non-invasive Raman-Trapping microscopy

Analysis of single cells is never easy – and it gets even more difficult when cells are not fixed at a surface but freely moving. In this case, Raman-Trapping-Microscopy arrests motile samples during spectral analysis. These most powerful devices enable novel insights into characteristics and ...

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Where theory and practice come together

Continuous manufacturing in the pharmaceutical industry

The question should not be why is the pharmaceutical industry beginning to engage in continuous manufacturing (CM), but rather “what took so long?” Essentially every other industry has been producing materials continuously for decades. Henry Ford began using the assembly line on December 1st, ...

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Translation

Innovations from the lab to commercial application

The structure of the big chemical and pharmaceutical companies has changed. Traditional centralised research departments conducting fundamental research have fallen victim to economic considerations. In exchange, young, dynamic start-up enterprises are increasingly brightening up the scene. This ...

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Biopharmaceuticals…

Everyday drugs for all?

There are currently several very good reasons to take a closer look at biopharmaceuticals. After the introduction of „modern biologicals“ at the beginning of the 1990s, including antibodies versus tumor necrosis factor (infliximab, adalimumab), more affordable generics/“biosimilars“ are ...

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Perspectives of Computer-Aided Drug Design

Working with models, namely three-dimensional illustrations of reality, is an integral part of any industrial design process. ­However, can we also use ‘design’ in relation to drug research? What is our understanding of these techniques today?

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The Future Field of Translational Medicine

Research at the interface between fundamentals and application

Medical progress is facing a crisis: the significant investments into the development of new therapies in recent years have not resulted in an increase in approvals of innovative drugs. The number of newly launched medications has already been stagnating for some time, although pharmaceutical ...

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Paradigm shift

Setting the course in genetic diagnostics and personalised medicine

What would medicine be without drugs? But are these drugs being used optimally today? Not at all, as we now know thanks to the findings of molecular medicine. Because for the use of these drugs, it is important to observe two aspects: the disease and the patient. Only slowly is it becoming ...

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Fit and healthy to 120

Not least thanks to bioanalysis!

I turned 63 recently. My secret to staying optimistic as you age towards your inevitable death? “The idea is to die young, but as late as humanly possible…” A noble aim, indeed…

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The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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