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ICH Linearity Studies using Automated Standard Preparation and UHPLC

According to the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), it is necessary to test analytical methods for their linearity as part of a method validation study. The typical process for this is to prepare standards ...

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Investment for the Future

Quality training pays off

This is a very particular concern and at the same time the demand placed annually on Dr. Irmgard Werner, who, as a lecturer at the ETH Zurich, supports around 65 pharmacy students in the 5th semester practical training in “pharmaceutical analysis”. With joy and enthusiasm for her subject she ...

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The Right Weight*

The new world of automated dosing

Every scientist studying at university was confronted in chemical practicals with the problem of dissolving a given powdered substance in a given solution and producing a solution with the prescribed ­concentration. The first step was to weigh. Armed with a spatula and a small sheet of weighing ...

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Thinking in Models

How do innovations come about?

Whether at home or in the office, our modern lives would be unthinkable without IT and electrical engineering. For industrial manufacturing, the rapid advances made in information and data processing technologies are the drivers of innovation, enabling intelligently controlled, automated ...

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Macromolecular environments influence proteins

Studying proteins in the presence of high concentrations of macromolecules (“molecular crowding”) with the aid of confocal fluorescence microscopy

The high-intensity interaction of proteins with other macromolecules can cause signifi cant changes to protein properties such as translational mobility, for example, or their conformational states. Accordingly, the study of proteins in macromolecular environments that typically very closely ...

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Authentic food

Why a single analysis parameter is not enough

Authentic food is growing in popularity with consumers. In a heavily industrialized market, a regional, single-source and/or specially manufactured product is increasingly becoming a guarantor of greater value. In the premium segment in particular, economically motivated “food fraud” can reap ...

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Fitness test of motile cells

Label-free and non-invasive Raman-Trapping microscopy

Analysis of single cells is never easy – and it gets even more difficult when cells are not fixed at a surface but freely moving. In this case, Raman-Trapping-Microscopy arrests motile samples during spectral analysis. These most powerful devices enable novel insights into characteristics and ...

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Where theory and practice come together

Continuous manufacturing in the pharmaceutical industry

The question should not be why is the pharmaceutical industry beginning to engage in continuous manufacturing (CM), but rather “what took so long?” Essentially every other industry has been producing materials continuously for decades. Henry Ford began using the assembly line on December 1st, ...

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Accurate weighing results

GWP® (Good Weighing Practice™) Life Cycle Management – 5 steps that support the Lean principles perfectly

A Lean Laboratory focuses on testing products and materials to deliver results in the most efficient way in terms of cost and speed. An accurate result for the customer is a pre-requisite. However, to guarantee accuracy of a weighing device over time requires using the correct balance as well as ...

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Translation

Innovations from the lab to commercial application

The structure of the big chemical and pharmaceutical companies has changed. Traditional centralised research departments conducting fundamental research have fallen victim to economic considerations. In exchange, young, dynamic start-up enterprises are increasingly brightening up the scene. This ...

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q&more – the networking platform for quality excellence in lab and process

The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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