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Alzheimer's: searching for a way out

Chemical synthesis of the tau protein to develop new active substances

Although the discovery of Alzheimer's disease now lies over a century in the past, the crucial events that influence the course of the disorder remain largely unknown. For some time now, researchers have been turning their attention to the tau protein, long known to be a component of deposits ...

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Learning from insects

Insect biotechnology as a means of exploiting biotechnology for the bioeconomy

With over a million documented species, insects are the most successful group of organisms from the perspective of biodiversity. In the course of their evolution, they have developed a giant arsenal of active ingredients and enzymes, which they use to defend themselves against enemies and disease ...

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Polar and a potential drinking water hazard

Analyzing drinking water for hazardous chemicals such as 1,4-dioxane

In Germany, drinking water supplies are plentiful and generally of a high quality. Drinking water is in Germany most commonly produced from groundwater (69.6 %), with a further 12.4 % being taken from lakes and dam reservoirs. The proportion of drinking water processed from bank filtration is ...

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Change as “continuous improvement”?

Accreditation requirements for laboratories

Several key international standards for laboratories are currently being revised, of which DIN EN ISO/IEC 17025 [1] is probably the most important. This will involve a number of changes for laboratories. Independently of revisions to standards, however, accreditation bodies are also ...

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Conductance or admittance?

Admittance detector: Exploration for high impedance capillary systems

Conductance detection is especially suited for charged compounds of small size that are otherwise difficult to detect because they do not have good optical absorption, notable examples are inorganic and small organic ions. By revisiting the principles of what was once called oscillometry and more ...

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“Work smarter, not harder”

Lean methods come to the lab…at last!

Is “lean lab“ just a management trend du jour or something which you need to carefully consider? The successful introduction of lean manufacturing into industrial production was completed years ago and is now an indispensable part of today’s highly competitive markets.

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Drug substances in the drug product dossier

Quality documentation requirements for marketing authorizations of medicinal products in Europe

Drug substances for drug products sold on the European market are now manufactured around the world. Regardless of the substance’s origin, the documentation of its pharmaceutical quality forms an important part of the drug product dossier and thus the prerequisites for a successful marketing ...

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Process excellence in the spotlight

Greater efficiency with Lean Management

Based on the successes achieved by the Toyota Production System, the concept of lean (i.e. streamlined) manufacturing has become established internationally since the 1990s. The topic is now becoming increasingly relevant for a highly-­regulated sector of industry in which the focus is on maximum ...

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Pollutants in ocean-floor sediment

New measurement methods to protect the marine environment

What kinds of contaminants are enriched in sediment – and are these then absorbed by the organisms that live there? What role do microplastics play? To answer these questions, Professor Gesine Witt’s team is using pollutant samplers made from silicone-coated glass fibre to investigate the sea ...

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A door to the future

Personalised oral pharmaceutical dosage forms via mass-customisation manufacturing

Managing the administration of multiple medications comprises an important part of global healthcare. Present pharmaceutical products do not easily allow for regimen adherence by patients or dosage customisation by physicians. A novel technology is being developed to provide personalised ...

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The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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