Within the various domains of life, the evolution of the tRNA processing enzyme (RNase P) has led to a set of highly diverse architectonic solutions. Bacterial RNase P thus has a fundamentally different structure to human RNase P enzymes in the cell nucleus and mitochondria. This structural ... more
Prof. Dr. Roland K. Hartmann
Philipps-Universität Marburg, Institut für Pharmazeutische Chemie
Roland K. Hartmann is Professor of Pharmaceutical Chemistry at the Philipps University of Marburg. He studied biochemistry at the Freie Universität Berlin, where he was awarded the Ernst Reuter Prize in 1988 for his outstanding dissertation work. His research interests include ribozymes (and RNase P in particular), regulatory RNAs, RNA viruses, RNA-protein and RNA-small ligand interactions, aptamers, antisense nucleic acids and RNA interference in an oncological context.