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Philipps-Universität Marburg, Institut für Pharmazeutische Chemie
Roland K. Hartmann is Professor of Pharmaceutical Chemistry at the Philipps University of Marburg. He studied biochemistry at the Freie Universität Berlin, where he was awarded the Ernst Reuter Prize in 1988 for his outstanding dissertation work. His research interests include ribozymes (and RNase P in particular), regulatory RNAs, RNA viruses, RNA-protein and RNA-small ligand interactions, aptamers, antisense nucleic acids and RNA interference in an oncological context.
Within the various domains of life, the evolution of the tRNA processing enzyme (RNase P) has led to a set of highly diverse architectonic solutions. Bacterial RNase P thus has a (…)
Anti-tumor agent from the intestine
It is believed to be involved in the development of chronic inflammatory intestinal diseases, to trigger diabetes, to be responsible for obesity, even neurological diseases such as multiple sclerosis and Parkinson's could have their causes here – not to mention depressions and autistic diso ... more
Just a few atoms thick: New functional materials developed
They are 50,000 times thinner than a human hair, and just a few atoms thick: two-dimensional materials are the thinnest substances it is possible to make today. They have completely new properties and are regarded as the next major step in modern semiconductor technology. In the future they ... more
New SARS-CoV-2 neutralizing antibody enters clinical phase
Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim announced the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody. By combining UKK, UMR and DZIF’s exper ... more
From RNA World to Protein World
Within the various domains of life, the evolution of the tRNA processing enzyme (RNase P) has led to a set of highly diverse architectonic solutions. Bacterial RNase P thus has a fundamentally different structure to human RNase P enzymes in the cell nucleus and mitochondria. This structural ... more
Dennis Walczyk studied chemistry at the Philipps University Marburg. From 2012, he has worked as a research assistant and doctoral candidate in the research group headed by Prof. Dr. Hartmann at the Institute for Pharmaceutical Chemistry at the University of Marburg, where he has been focus ... more
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