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Dr. Klaus Fritsch

Mettler-Toledo GmbH

Dr. Klaus Fritsch

Klaus Fritsch is Manager Compliance of the Global Business Area “Laboratory Weighing” within Mettler-Toledo. He has been with Mettler-Toledo since 2005, acting as senior metrologist and consulting the industry to achieve compliance with applicable regulations when using weighing instruments. He received his Ph.D. in Physics by the Technical University of Munich, Germany, in 1997. Prior to joining Mettler-Toledo, he worked as a consultant for the pharmaceutical and chemical industry, mainly focusing on risk management and process safety.


Fritsch is USP Expert Advisor for the General Chapters 41 and 1251, member of the Ph. Eur. Expert Group for General Chapter 2.1.7, the EURAMET technical committee responsible for the calibration guideline cg-18 on Non-automatic Weighing Instruments, and a working group of the ASTM International Committee E41 that targets balance calibration and testing. He is furthermore active in several ISO working groups, for example the ISO/TC48 subcommittee responsible for volumetric apparatus, thereby focusing on pipette calibration.


The objective of his work is to ensure that the metrological concepts and requirements stipulated by the various standards are sound but still easy to adapt by the industry. He is building a bridge between standard-setting organizations, national metrological institutes and the industries that are affected by the regulations.

Facts, background information, dossiers

  • pipette calibration
  • balance calibration

Other articles by this author

All articles

New Requirements

The U.S. Pharmacopoeia Convention (USP) has recently published a revised version of its mandatory chapter 41 (Balances) plus amendments to chapter 1251 (Weighing on an Analytical Balance (…)

Weighing in the US Pharmacopeia

Weighing is one of the key activities carried out in every QC laboratory. Usually, it is one of the first parts of a whole analysis chain. As any weighing errors have the potential to (…)

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