Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now succeeded in changing these enzymes so that entirely new natural produ ... more
Prof. Dr. Heinfried H. Radeke
Johann Wolfgang Goethe-Universität Frankfurt (Main), Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie
Heinfried H. Radeke studied medicine at the Hannover Medical School (MHH) and received his medical license in 1985. His Ph.D. thesis was recognized as the best research dissertation of 1986. After two years as an assistant physician at the Göttingen University Hospital, he began his career at MHH in 1987 with his research focus: the mechanisms of chronic inflammation in the field of molecular pharmacology. He completed his habilitation in this field in 1993 before further specializing as a consultant for general pharmacology and toxicology, consultant immunologist (DGfI), and consultant for clinical pharmacology (Frankfurt, 2004).
Following a four-month research project at BASF Bioresearch in Cambridge (Boston) in 1992, Heinfried Radeke spent the period 1994–1997 completing further DFG-sponsored research in the USA. This involved one year at UC San Francisco (interleukin-1 alpha and carcinogenesis), followed by two years at Case Western Reserve University in Cleveland (nephritis, differentiation of T cells). Since 2001, Prof. Radeke has been aiding the realignment of pharmazentrum frankfurt (Prof. Josef M. Pfeilschifter, dean of medical faculty and director of the Institute of General Pharmacology and Toxicology) towards immunopharmacology, from 2001 to 2008 as the Dr. Hans Schleussner Foundation Lecturer for Immunopharmacology. He plays a decisive role in the training of medical and dental students, with past positions including that of deputy director of the DFG’s largest research training group, GRK1172 Biologicals, in which over 100 doctorates were awarded from 2005 – 2014.