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Friedrich-Schiller-Universität Jena, Institut für Pharmazie & Jena Center for Soft Matter
Dagmar Fischer is a licensed pharmacist before obtaining her doctorate in pharmaceutical technology and biopharmacy from the Philipps University of Marburg in 1997. After a period spent at Texas Tech University Health Sciences Center (USA), she gained several years' experience as Head of Preclinical Research & Development at Antisense Pharma GmbH before accepting a professorship in Pharmaceutical Technology at Friedrich Schiller University Jena in 2008.
Activities
Dagmar Fischer plays an active role in numerous scientific societies and organizations, including as Secretary General of the German Pharmaceutical Society (DPhG), Deputy Director and Member of the Jena Center for Soft Matter (JCSM), Founding Ambassador of the FSU Jena for the Faculty of Biological Sciences. She is also a member of the International Association for Pharmaceutical Technology (APV) and its Division “Education and Science” as well as the Controlled Release Society (CRS) Local Chapter Germany.
Focus
Her work focuses on the development of nanoparticulate drug delivery systems from natural and synthetic polymers as well as their testing in biopharmaceutical 2D and 3D in vitro models to characterize the drug transport in the body. A major topic is related to the aspect of nanosafety including the development of alternative animal methods according to the 3R concept.
Methods
The targeted transport of DNA and RNA using vectors (mostly made from synthetic polymers) in cell cultures has become part of routine practice in biological R&D – a fact highlighted by the (…)
How the first biomolecules could have been formed
The chemical precursors of present-day biomolecules could have formed not only in the deep sea at hydrothermal vents, but also in warm ponds on the Earth's surface. The chemical reactions that may have occurred in this “primordial soup” have now been reproduced in experiments by an internat ... more
Fitness needs the right timing
Life on Earth runs in 24-hour cycles. From tiny bacteria to human beings, organisms adapt to alterations of day and night. External factors, such as changes in light and temperature, are needed to entrain the clock. Many metabolic processes are controlled by the endogenous clock. Scientists ... more
Catalytic hydrogen generation – without expensive precious metals
A research team from Friedrich Schiller University Jena has developed a molecular photosystem inspired by nature that generates hydrogen under visible light irradiation. In contrast to other existing systems of this type, it functions without the use of precious or heavy metals. Low-cost an ... more
Effective drug navigation in sepsis
Many drug candidates never reach clinical use due to their side effects. For example, inhibitors of phosphoinositide 3-kinase-γ, a signaling protein that plays an important role in infections, cannot be used because of their side effects on the immune response. more
The targeted transport of DNA and RNA using vectors (mostly made from synthetic polymers) in cell cultures has become part of routine practice in biological R&D – a fact highlighted by the multitude of commercial kits now available. To date, however, obstacles relating to use in patients ha ... more
The isolation of bioactive plant ingredients, essential oils or dyes and flavourings of plant origin requires costly and sophisticated procedures. Several applications do not actually require isolation of the individual components, however – their concentration is sufficient. Moreover, for ... more
Ulrich S. Schubert, born in 1969, is Chair (W3) for Organic and Macromolecular Chemistry at Friedrich Schiller University Jena, Germany. He studied chemistry at the Universities of Frankfurt and Bayreuth and subsequently received his PhD from the Universities of Bayreuth and South Florida, ... more
Thomas Heinze, born in 1958, studied chemistry at FSU Jena. After receiving his doctorate there in 1989 and subsequent postdoc work at KU Leuven (Belgium), he completed his habilitation in 1997. In 2001, he accepted a professorship in Macromolecular Chemistry at the University of Wuppertal ... more
Prof. Dr. Gerhard K. E. Scriba
born 1956, studied pharmacy in Bonn and in 1980 received the licence to practise pharmacy. He received his doctorate in 1984 at the Westphalian Wilhelms-University in Munster, where, in 1995, he qualified as a professor in the subject of pharmaceutical chemistry. In 1999 he was appointed to ... more
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