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Author

Prof. Dr. Dagmar Fischer

Friedrich-Schiller-Universität Jena, Institut für Pharmazie & Jena Center for Soft Matter

Prof. Dr. Dagmar Fischer

Dagmar Fischer is a licensed pharmacist before obtaining her doctorate in pharmaceutical technology and biopharmacy from the Philipps University of Marburg in 1997. After a period spent at Texas Tech University Health Sciences Center (USA), she gained several years' experience as Head of Preclinical Research & Development at Antisense Pharma GmbH before accepting a professorship in Pharmaceutical Technology at Friedrich Schiller University Jena in 2008.

Activities

Dagmar Fischer plays an active role in numerous scientific societies and organizations, including as Secretary General of the German Pharmaceutical Society (DPhG), Deputy Director and Member of the Jena Center for Soft Matter (JCSM), Founding Ambassador of the FSU Jena for the Faculty of Biological Sciences. She is also a member of the International Association for Pharmaceutical Technology (APV) and its Division “Education and Science” as well as the Controlled Release Society (CRS) Local Chapter Germany.

Focus

Her work focuses on the development of nanoparticulate drug delivery systems from natural and synthetic polymers as well as their testing in biopharmaceutical 2D and 3D in vitro models to characterize the drug transport in the body. A major topic is related to the aspect of nanosafety including the development of alternative animal methods according to the 3R concept.

Methods

  • Techniques to formulate nanoparticles in lab scale and upscale
  • Physicochemical characterization to describe nanoparticle characteristics including stability and degradation in physiological and simulated body fluids
  • Biological short-term and long-term tests in cell culture, gene delivery and microbiology laboratories in skin, lung, intestine, tumor and blood brain barrier models
  • Investigations using a shell-less hen’s egg model (toxicity, distribution, stability)
  • Safe by design concepts
  • GxP concepts and process development

Facts, background information, dossiers

Other articles by this author

All articles

Genes on sugar

The targeted transport of DNA and RNA using vectors (mostly made from synthetic polymers) in cell cultures has become part of routine practice in biological R&D – a fact highlighted by the (…)

More about Uni Jena

  • News

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    A new algorithm has been designed to help discover previously unknown material compounds. It was developed by a team from Martin Luther University Halle-Wittenberg (MLU), Friedrich Schiller University Jena and Lund University in Sweden. The researchers designed a form of artificial intellig ... more

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    More than a third of all medicines available today are based on active substances from nature and a research team from the University of Jena has developed a procedure to identify small active substance molecules much more quickly and easily. Secondary natural substances that occur in numer ... more

    Small molecules with a dual function

    The human gut is a multi-species habitat that can control our health and well-being. Bacteria, viruses and microbial fungi are part of this complex microbial community and help us with our digestion and immune defense. If the intestinal flora is impaired, for example by contaminated drinkin ... more

  • q&more articles

    Genes on sugar

    The targeted transport of DNA and RNA using vectors (mostly made from synthetic polymers) in cell cultures has become part of routine practice in biological R&D – a fact highlighted by the multitude of commercial kits now available. To date, however, obstacles relating to use in patients ha ... more

    Highly-prized components

    The isolation of bioactive plant ingredients, essential oils or dyes and flavourings of plant origin requires costly and sophisticated procedures. Several applications do not actually require isolation of the individual components, however – their concentration is sufficient. Moreover, for ... more

    Molecules in the mirror

    In 1871 the children‘s book “Through the Looking-Glass – And What Alice Found There” by the English author Lewis Carroll, in which Alice enters a world behind the mirror, was published. She explains to her cat: “First there’s the room you can see through the glass – that’s just the same as ... more

  • Authors

    Prof. Dr. Ulrich S. Schubert

    Ulrich S. Schubert, born in 1969, is Chair (W3) for Organic and Macromolecular Chemistry at Friedrich Schiller University Jena, Germany. He studied chemistry at the Universities of Frankfurt and Bayreuth and subsequently received his PhD from the Universities of Bayreuth and South Florida, ... more

    Prof. Dr. Thomas Heinze

    Thomas Heinze, born in 1958, studied chemistry at FSU Jena. After receiving his doctorate there in 1989 and subsequent postdoc work at KU Leuven (Belgium), he completed his habilitation in 1997. In 2001, he accepted a professorship in Macromolecular Chemistry at the University of Wuppertal ... more

    Prof. Dr. Gerhard K. E. Scriba

    born 1956, studied pharmacy in Bonn and in 1980 received the licence to practise pharmacy. He received his doctorate in 1984 at the Westphalian Wilhelms-University in Munster, where, in 1995, he qualified as a professor in the subject of pharmaceutical chemistry. In 1999 he was appointed to ... more

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