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Johann Wolfgang Goethe-Universität Frankfurt (Main), Institut für Molekulare Biowissenschaften
Jörg Soppa, born in 1958, studied biochemistry in Tübingen and then went on to do his doctorate at the Max Planck Institute of Biochemistry in Martinsried near Munich. In 1990 he established his own research group there and held courses at the Institute of Genetics and Microbiology of Munich University where, in 1994, he qualified as a professor. In 1995 he was a visiting scientist at the University of British Columbia in Vancouver. Soppa has been working at Frankfurt’s Goethe University since 1996, first as a Heisenberg fellow, and since 2001 as a professor of microbial genetics. His group investigates a variety of biological processes in archaea and bacteria.
Activities
For seven years, Soppa coordinated the Priority Program “Genome Function and Gene Regulation in Archaea” of the German Research Foundation (DFG). In addition, he took over many responsibilities within the department. For six years he was an academic dean. He was and is still a member of many university commissions and since 2013 also chairman of the university's accreditation commission for degree courses.
Awards
Jörg Soppa received a Heisenberg scholarship from the DFG in 1995. In 2010, he was selected by the students of the Goethe University as the best biology lecturer.
Focus
Jörg Soppa’s research group works in basic research and focuses mainly on halophilic archaea, which live in biotopes containing high salt concentrations. It uses molecular genetic, microbiological and biochemical methods to investigate, for example, the regulation processes that enable adaptation to different conditions. Other fields of research include small, non-coding RNAs, very small proteins (μ proteins) and the initiation of translation. With its discovery that most prokaryotic species contain several or numerous genome copies (and are thus oligoploid or polyploid), the research group has set new standards.
Methods
Bacteria are true survivors. In the course of evolution, they have developed numerous strategies to adapt to rapidly changing, uncertain environmental conditions. Their metabolism is much (…)
Immunologists Frederick W. Alt (73) of Harvard Medical School and David G. Schatz (64) of Yale School of Medicine are to receive the 2023 Paul Ehrlich and Ludwig Darmstaedter Prize, as the Scientific Council of the Paul Ehrlich Foundation announced. The two researchers are being acknowledge ... more
How do killer T cells know where danger is coming from?
How do killer T cells recognise cells in the body that have been infected by viruses? Matter foreign to the body is presented on the surface of these cells as antigens that act as a kind of road sign. A network of accessory proteins – the chaperones – ensure that this sign retains its stabi ... more
Laboratory study: effect of antibodies against omicron variants BA.1 and BA.2 wears off quickly
The omicron variants BA.1 and BA.2 of the SARS-CoV-2 virus, which are dominant from about December to April, can undermine the protection against infection offered by vaccinations or survived infections after only three months. This is shown by a study from Frankfurt under the leadership of ... more
From feast to famine and back – no problem for bacteria
Bacteria are true survivors. In the course of evolution, they have developed numerous strategies to adapt to rapidly changing, uncertain environmental conditions. Their metabolism is much more sophisticated than that of human beings. Within minutes they can regulate their gene expression an ... more
Why biosimilars and not biogenerics?
Medicines produced using genetic techniques have existed since 2006, called “similar biological medicinal products” or “biosimilars”. Until a year ago, this was a fairly low-profile group, even in expert circles. This has all changed now, however, with the recent licensing of the first bios ... more
What would medicine be without drugs? But are these drugs being used optimally today? Not at all, as we now know thanks to the findings of molecular medicine. Because for the use of these drugs, it is important to observe two aspects: the disease and the patient. Only slowly is it becom ... more
Claudia Büchel, born in 1962, studied biology at the University of Mainz, where she also received her doctorate and, in 2001, the qualification to teach plant physiology. After a postdoctoral research period at the Biological Research Centre, Szeged, she worked for four years as a research ... more
Heinfried H. Radeke studied medicine at the Hannover Medical School (MHH) and received his medical license in 1985. His Ph.D. thesis was recognized as the best research dissertation of 1986. After two years as an assistant physician at the Göttingen University Hospital, he began his career ... more
Theodor Dingermann, born 1948, studied pharmacy in Erlangen and received his doctor title in 1980 to become Dr. rer. nat. In 1990 he was offered the C4 professorship at the Institute for Pharmaceutical Biology, University of Frankfurt. From 2000 to 2004 he was President of the German Phar ... more
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