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Dr. Christian Derntl

Technische Universität Wien, Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften

Theresa Radebner

Mag. Dr. Christian Derntl

Christian Derntl, born in 1983, completed his diploma studies in microbiology and immunology at the University of Vienna. In 2014, he completed his PhD study in technical chemistry with distinction at TU Wien. The topic of his thesis was the regulation of cellulases in the fungus Trichoderma reesei. In the following years, Christian Derntl remained at TU Wien and worked on the development of an artificial gene expression system in industrial fungi. In a side project he focused on the secondary metabolism in fungi, in which he acquired further valuable experience in 2017 and 2018 as a postdoc at Vienna’s University of Natural Resources and Life Sciences in the research group “Metabolomics and Bioactive Substances”. Subsequently, Christian Derntl returned to TU Wien to work as a university assistant, and since 2021 as a senior scientist in the research group “Synthetic Biology and Molecular Biotechnology”.


Every problem has at least one solution.


Christian Derntl currently leads projects on “ribosomally synthesized and post-translationally modified peptides” (RiPPs) and the regulatory network for morphology and the secondary metabolism in fungi. The scientific topics cover various bioinformatics and biotechnological approaches to discover novel secondary metabolites. An important aspect is the development and establishment of different methods for efficient strain design. Christian Derntl is also involved in teaching at TU Wien, giving lectures in biology, microbiology, biochemistry and biotechnology.


Christian Derntl’s scientific focus is the discovery of novel secondary metabolites from fungi.


  • Molecular biology
  • Microbiology
  • Synthetic biology
  • Genome editing (CRISPR/Cas)
  • Bioinformatics
  • Transcriptomics
  • Enzyme characterization

Facts, background information, dossiers

  • microbiology
  • immunology
  • technical chemistry
  • fungi
  • secondary metabolites
  • metabolomics
  • synthetic biology
  • molecular biotechnology
  • bioinformatics
  • biotechnology
  • strain design
  • molecular biology
  • genome editing
  • transcriptomics
  • Enzyme characterization
  • enzyme characterization

Other articles by this author

All articles

The search for APIs in the genome of fungi

Fungi hold enormous potential to discover new active pharmaceutical ingredients (APIs) and valua-ble substances, for example antibiotics, pigments and raw materials for biological plastics (…)

More about TU Wien

  • News

    Bacteria as climate heroes

    To establish a carbon-neutral circular economy in the future, technologies are needed that use carbon dioxide as a raw material. In the form of formate, CO2 can be metabolised by certain bacteria. Acetogens are a group of bacteria that can metabolise formate. For example, they form acetic a ... more

    Tuneable Catalysis: Solving the Particle Size Puzzle

    Chemical reactions can be studied at different levels: At the level of individual atoms and molecules, new compounds can be designed. At the level of tiny particles on the nano and micrometre scale, one can understand how catalyst materials influence chemical reactions. And in order to use ... more

    Anchoring single atoms

    There is a dictum to “never change a running system”. New methods can however be far superior to older ones. While to date chemical reactions are mainly accelerated by catalytic materials that comprise several hundreds of atoms, the use of single atoms could provide a new approach for catal ... more

  • Authors

    Sarah Spitz

    Sarah Spitz, born in 1993, studied biotechnology at the University of Natural Resources and Applied Life Sciences (BOKU) in Vienna, graduating with an engineering diploma degree. While studying, she was employed for two years as a research assistant at the Department of Biotechnology (DBT) ... more

    Prof. Dr. Peter Ertl

    Peter Ertl, born in 1970, studied food and biotechnology at the University of Natural Resources and Applied Life Sciences, Vienna. He obtained a PhD in chemistry from the University of Waterloo, Canada, and subsequently spent several years as a postdoc at the University of California at Ber ... more

    Dr. Kurt Brunner

    Kurt Brunner, born in 1973 graduated in Technical Chemistry from TU Vienna before obtaining his doctorate from the University’s Institute of Chemical Engineering in 2003. While preparing his thesis, he worked on the molecular biology of fungi. Following research work conducted at the Univer ... more

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