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Dr. Christian Derntl

Technische Universität Wien, Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften

Theresa Radebner

Mag. Dr. Christian Derntl

Christian Derntl, born in 1983, completed his diploma studies in microbiology and immunology at the University of Vienna. In 2014, he completed his PhD study in technical chemistry with distinction at TU Wien. The topic of his thesis was the regulation of cellulases in the fungus Trichoderma reesei. In the following years, Christian Derntl remained at TU Wien and worked on the development of an artificial gene expression system in industrial fungi. In a side project he focused on the secondary metabolism in fungi, in which he acquired further valuable experience in 2017 and 2018 as a postdoc at Vienna’s University of Natural Resources and Life Sciences in the research group “Metabolomics and Bioactive Substances”. Subsequently, Christian Derntl returned to TU Wien to work as a university assistant, and since 2021 as a senior scientist in the research group “Synthetic Biology and Molecular Biotechnology”.


Every problem has at least one solution.


Christian Derntl currently leads projects on “ribosomally synthesized and post-translationally modified peptides” (RiPPs) and the regulatory network for morphology and the secondary metabolism in fungi. The scientific topics cover various bioinformatics and biotechnological approaches to discover novel secondary metabolites. An important aspect is the development and establishment of different methods for efficient strain design. Christian Derntl is also involved in teaching at TU Wien, giving lectures in biology, microbiology, biochemistry and biotechnology.


Christian Derntl’s scientific focus is the discovery of novel secondary metabolites from fungi.


  • Molecular biology
  • Microbiology
  • Synthetic biology
  • Genome editing (CRISPR/Cas)
  • Bioinformatics
  • Transcriptomics
  • Enzyme characterization

Facts, background information, dossiers

  • microbiology
  • immunology
  • technical chemistry
  • fungi
  • secondary metabolites
  • metabolomics
  • synthetic biology
  • molecular biotechnology
  • bioinformatics
  • biotechnology
  • strain design
  • molecular biology
  • genome editing
  • transcriptomics
  • Enzyme characterization
  • enzyme characterization

Other articles by this author

All articles

The search for APIs in the genome of fungi

Fungi hold enormous potential to discover new active pharmaceutical ingredients (APIs) and valuable substances, for example antibiotics, pigments and raw materials for biological plastics (…)

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    The search for APIs in the genome of fungi

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