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19 Current news of Charité
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Preventing spread of SARS coronavirus-2 in humans
Infection researchers identify potential drug
09-Mar-2020
Viruses must enter cells of the human body to cause disease. For this, they attach to suitable cells and inject their genetic information into these cells. Infection biologists from the German Primate Center - Leibniz Institute for Primate Research in Göttingen, together with colleagues at ...
Hundreds of novel viruses discovered in insects
10-Jan-2020
New viruses which cause diseases often come from animals. Well-known examples of this are the Zika virus transmitted by mosquitoes, bird flu viruses, as well as the MERS virus which is associated with camels. In order to identify new viral diseases quickly and prevent possible epidemics, DZIF ...
DNA saturation mutagenesis: Identifying which mutations really cause disease
15-Aug-2019
Scientists at the Berlin Institute of Health (BIH) and Charité – Universitätsmedizin Berlin, working with colleagues from the United States, have selectively modified the control regions of 20 disease-relevant genes. This enabled them to identify precisely those modifications that have the ...
Stem cells moonlight to protect the stomach from bacterial invaders
A subpopulation of stem cells releases antimicrobial peptides to defend the gastric mucosa against pathogenic bacteria
01-Jul-2019
Our mucosal surfaces are constantly exposed to numerous bacterial species, some of which can induce DNA damage in host cells. Normally this remains inconsequential, as the rapid turnover of the mucosa means damaged cells are shed within days. However, if the long-lived stem cells that continually ...
How Artificial Intelligence Detects Rare Diseases
11-Jun-2019
Every year, around half a million children worldwide are born with a rare hereditary disease. Obtaining a definitive diagnosis can be difficult and time consuming. In a study of 679 patients with 105 different rare diseases, scientists from the University of Bonn and the Charité - ...
Prostate cancer – New computer model enables researchers to predict course of disease
18-Dec-2018
How does a normal cell turn into a deadly cancer? Seeking an answer to this question, and working alongside other international working groups, researchers from Charité – Universitätsmedizin Berlin examined the tumor genomes of nearly 300 prostate cancer patients. Their findings describe the ways ...
Quality control inside the cell
How rescue proteins dispose of harmful messages
23-Jan-2017
The ability to dispose of proteins that are either aberrant or (in the worst case) toxic is fundamental to a cell's survival. Researchers from Charité - Universitätsmedizin Berlin have been able to demonstrate the manner in which two specific proteins recognize defective messenger RNAs (molecules ...
Nanostructures in human teeth
06-Jun-2016
Dentin is one of the most durable biological materials in the human body. Researchers from Charité–Universitätsmedizin Berlin were able to show that the reason for this can be traced to its nanostructures and specifically to the interactions between the organic and inorganic components. ...
Strong teeth: Nanostructures under stress make teeth crack resistant
16-Jun-2015
Human teeth have to serve for a lifetime, despite being subjected to huge forces. But the high failure resistance of dentin in teeth is not fully understood. An interdisciplinary team led by scientists of Charite Universitaetsmedizin Berlin has now analyzed the complex structure of dentin. At the ...
q&more – the networking platform for quality excellence in lab and process
The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.
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