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8 Current news of European Molecular Biology Laboratory
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Melting reveals drug targets in a living organism
Scientists identify drug targets in blood and organs
23-Jan-2020
Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. An international team led by researchers at the European Molecular Biology Laboratory and Cellzome, a GSK company, has developed a technology to ...
Toxin responsible for Legionella growth identified
24-Jul-2019
A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps legionella grow inside human cells. SidJ hijacks human protein Calmodulin ...
Snapshots of the flu virus replication machine in action
05-Jun-2019
Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, provide valuable information for the next generation of anti-influenza ...
Designer organelles bring new functionalities into cells
EMBL scientists create membraneless organelle to build proteins in living cell
01-Apr-2019
For the first time, scientists have engineered the complex biological process of translation into a designer organelle in a living mammalian s. Research by the Lemke group at the European Molecular Biology Laboratory (EMBL) – in collaboration with JGU Mainz and IMB Mainz – used this technique to ...
New Ways to Look at Protein-RNA Networks
10-Dec-2018
For their vital tasks, all RNA molecules in our cells require proteins as binding partners. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and colleagues from the European Molecular Biology Laboratory (EMBL) have developed the first method with which they ...
Combining antibiotics changes their effectiveness
06-Jul-2018
The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives. Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance, ...
Detailed structure of cell’s garbage disposal unit reveals surprise in how it is targeted by cancer drugs
Every atom counts
08-Aug-2016
Malignant cancer cells not only proliferate faster than most healthy cells in our bodies. They also generate more “junk”, such as faulty and damaged proteins. This makes cancer cells inherently more dependent on the most important cellular garbage disposal unit, the proteasome, which degrades ...
Scientists X-ray protein crystals inside cells
Novel approach to unveil the structure of challenging biomolecules
22-Jan-2016
Scientists from the European Molecular Biology Laboratory EMBL have teamed up with experts from DESY and the U.S. SLAC National Accelerator Laboratory to X-ray protein crystals naturally produced within biological cells. The study at the world's currently most powerful X-ray laser LCLS at SLAC ...
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