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Modern humans developed a more effective protection against oxidative stress

Neanderthal variant of the protein glutathione reductase increases risk for inflammatory bowel disease and vascular disease

07-Jan-2022

Very few proteins in the body have a change that makes them unique compared to the corresponding proteins in Neanderthals and apes. Researchers at the Max Planck Institute for Evolutionary Anthropology in Germany and Karolinska Institutet in Sweden have now studied one such protein, glutathione ...

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New group of antibacterial molecules identified

International research group discovers promising scaffold for antimicrobial agents

19-Nov-2021

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria. Since the properties of the molecules can easily be altered chemically, the hope is to develop ...

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Nobel Prize in Physiology or Medicine 2021 awarded to US scientists David Julius and Ardem Patapoutian

How do we perceive the world?

04-Oct-2021

The Nobel Assembly at Karolinska Institutet has decided to award the 2021 Nobel Prize in Physiology or Medicine jointly to David Julius and Ardem Patapoutian for their discoveries of receptors for temperature and touch. Our ability to sense heat, cold and touch is essential for survival and ...

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Revealing the molecular mechanisms of the circadian clock

Nobel Prizes in Physiology or Medicine announced

02-Oct-2017

Life on Earth is adapted to the rotation of our planet. For many years we have known that living organisms, including humans, have an internal, biological clock that helps them anticipate and adapt to the regular rhythm of the day. But how does this clock actually work? Jeffrey C. Hall, Michael ...

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New nanoparticle technology to decipher structure and function of membrane proteins

10-Mar-2016

Researchers at Karolinska Institutet, Sweden, have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment. The method makes it possible to access drug targets that previously could not be investigated and ...

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