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A fine sense for molecules

Unique laser technology for the analysis of the molecular composition of biological samples

07-Jan-2020

At the biochemical level, organisms can be thought of as complex collections of different species of molecules. In the course of their metabolism, biological cells synthesize chemical compounds, and modify them in multifarious ways. Many of these products are released into the intercellular ...

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New algorithm detects even the smallest cancer metastases across the entire mouse body

Exposing the enemy

16-Dec-2019

Teams at Helmholtz Zentrum München, LMU Munich and the Technical University of Munich (TUM) have developed a new algorithm that enables automated detection of metastases at the level of single disseminated cancer cells in whole mice. Cancer is one of the leading causes of death worldwide. More ...

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Five-fold boost in formaldehyde yield

15-Nov-2019

Environmentally benign methods for the industrial production of chemicals are urgently needed. LMU researchers recently described such a procedure for the synthesis of formaldehyde, and have now improved it with the aid of machine learning. Formaldehyde is one of the most important feedstocks ...

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AI-driven single blood cell classification

New method to support physicians in leukemia diagnostics

14-Nov-2019

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood samples from patients suffering from acute myeloid leukemia (AML). Their proof of concept study paves ...

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An ultrafast glimpse of the photochemistry of the atmosphere

15-Oct-2019

Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have explored the initial consequences of the interaction of light with molecules on the surface of nanoscopic aerosols. The nanocosmos is constantly in motion. All natural processes are ultimately determined by the interplay between ...

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DNA repair: Opening the hatch to heal the break

05-Sep-2019

LMU researchers have determined the structure of a key enzyme complex that is involved in DNA repair, and traced the cycle of conformational changes that it undergoes while performing its biochemical function. Various types of DNA damage can have serious repercussions, both for the individual ...

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Alzheimer’s disease: Protective immune response in the brain?

02-Sep-2019

LMU researchers Christian Haass and Michael Ewers have identified a factor that might possibly delay the emergence and slow the progression of Alzheimer’s disease. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Institute for Stroke and Dementia Research (ISD) at ...

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One transistor for all purposes

Organic semiconductors

22-Mar-2019

In mobiles, fridges, planes – transistors are everywhere. But they often operate only within a restricted current range. LMU physicists have now developed an organic transistor that functions perfectly under both low and high currents. Transistors are semiconductor devices that control voltage ...

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Tiny “blinkers” reveal molecules inside cells

18-Mar-2019

LMU physicists led by Ralf Jungmann introduce an entirely new approach to super-resolution microscopy: Tiny ‘blinkers’ enable simultaneous imaging of multiple biomolecules. In everyday life, blinking lights can send signals – for example, that a car is going to turn. Now, researchers have ...

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Solid-state catalysis: Fluctuations clear the way

19-Feb-2019

LMU chemists have identified a mechanism that allows molecules to diffuse rapidly on the already crowded surface of a solid-state catalyst – an important capability, especially for efficient catalysis under industrial conditions. The use of efficient catalytic agents is what makes many technical ...

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