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Enzyme silences virus-like sequences

Methyltransferase Dnmt1 is not only responsible for maintenance

07-Jul-2021

Often, biology will not fit into clear-cut categories. In a recent publication, an enzyme to which researchers had previously assigned a distinct task is stepping outside its box. It not only maintains the epigenetic state of the genome, but can also specifically silence additional DNA segments ...

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Piecing together the full picture of the genome

Revolutionary new DNA sequencing method enables unparalleled rapid, accurate, and efficient analysis while preserving the full picture of a genome

17-Jun-2021

A team of international researchers from the Friedrich Miescher Laboratory of the Max Planck Society developed a new DNA sequencing method that provides fast and efficient tracking of genetic information. Their new technique called haplotagging now enables scientists to quickly and precisely ...

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Nucleosome breathing from atomistic time snapshots

Computer simulations visualize in atomic detail how DNA opens while wrapped around proteins

08-Jun-2021

Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in Münster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA opens while it is tightly wrapped around the proteins that package our ...

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Enantiomorph distribution maps for metals and metallic alloys

07-Jun-2021

The spatially resolved determination of which of the two enantiomorphic structural variants - the left-handed or the right-handed - of a chiral phase is present in a polycrystalline material is the focus of a publication in Science Advances. With the EBSD (electron backscatter diffraction) -based ...

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Researchers reveal another secret of photosynthesis

Chemical isomerism in Nature’s water splitting catalyst may explain the high efficiency of the photosynthetic reaction

01-Jun-2021

Green hydrogen is often said to be “the petroleum of tomorrow”. For a climate-neutral energy supply in the future, we must turn away from carbon-based sources and harness solar fuels. The road ahead is long and requires, among other things, a precise knowledge of the functional principles of ...

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In milliseconds from polluted to clear water

New discoveries in the field of nanoscience

19-May-2021

Researchers at the Max Planck Institute of Colloids and Interfaces developed a membrane that is composed of a bundle of nanometer-sized tubes. They used it as a nanoreactor to convert water marked with methylene blue into clear water in milliseconds using sunlight as a driver. ‘Running reactions ...

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Efficiently smuggling drugs into cells

New method makes it easier than before to test new therapies

17-May-2021

A new, patented method called Progressive Mechanoporation makes it possible to mechanically disrupt the membranes of cells for a short time period and let drugs or genes inside cells. In this way, researchers can test new therapies more easily than before. Modern vaccines such as those against ...

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Speeding up sequence alignment across the tree of life

A sequence search engine for a new era of conservation genomics

09-Apr-2021

A team of researchers from the Max Planck Institutes of Developmental Biology in Tübingen and the Max Planck Computing and Data Facility in Garching develops new search capabilities that will allow to compare the biochemical makeup of different species from across the tree of life. Its ...

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New microscopy method resolves fluorescent molecules with resolution at the nanometer scale

22-Mar-2021

Scientists working with Stefan Hell at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen and the Heidelberg-based MPI for Medical Research have developed another light microscopy method, called MINSTED, which resolves fluorescently labeled details with molecular sharpness. ...

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Cells talk at each other to specialize different functions

New concept to describe how cells specialize during development

23-Feb-2021

During development, cells must specialize their function in a well defined timeline: formation of different tissues must be coordinated from a pile of cells. The research group led by Aneta Koseska (former Max Planck Institute of Molecular Physiology (MPI), CAESAR Bonn) has now developed a new ...

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