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Structure of key protein for cell division puzzles researchers

Researchers provide a first 3D snapshot of the CCAN protein complex and raise fundamental questions towards the creation of artificial chromosomes

17-May-2022

Human cell division involves hundreds of proteins at its core. Knowing the 3D structure of these proteins is pivotal to understand how our genetic material is duplicated and passed through generations. The groups of Andrea Musacchio and Stefan Raunser at the Max Planck Institute of Molecular ...

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A new dimension in Stem Cell Signaling

Molecular morse code in stem cells encrypting differentiation information revealed

01-Mar-2022

Divide, differentiate or die? Making decisions at the right time and place is what defines a cell’s behavior and is particularly critical for stem cells of an developing organisms. Decision making relies on how information is processed by networks of signaling proteins. The teams around Christian ...

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Cool Microscopy: Making the invisible visible

Ultrarapid cooling enables the observation of molecular patterns of life

15-Dec-2021

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing movement of molecules and the light-induced destruction of ...

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Stem cells do not (only) play dice

Stem cells work as a team and do not leave their fate to pure chance

10-Nov-2021

In just a few weeks a completely new organism develops from a fertilized egg cell. The real miracle is that a bunch of identical stem cells turns into completely different, specialized cell types. A team led by Christian Schröter, group leader at the Max Planck Institute of Molecular Physiology ...

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Cells talk at each other to specialize different functions

New concept to describe how cells specialize during development

23-Feb-2021

During development, cells must specialize their function in a well defined timeline: formation of different tissues must be coordinated from a pile of cells. The research group led by Aneta Koseska (former Max Planck Institute of Molecular Physiology (MPI), CAESAR Bonn) has now developed a new ...

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Protein injections in medicine

One day, medical compounds could be introduced into cells with the help of bacterial toxins

18-Dec-2019

Pathogens can use a range of toxins to damage their host organism. Bacteria, such as those responsible for causing the deadly Plague, use a special injection mechanism to deliver their poisonous contents into the host cell. Stefan Raunser, Director at the Max Planck Institute for Molecular ...

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