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6 Current news of Paul-Ehrlich-Institut

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New Vaccine Platform for a Vaccination against Hepatitis B

Oral or Transdermal Vaccination Possible

03-Mar-2020

Scientists of the Paul-Ehrlich-Institut have researched a vaccine platform, which confers a very good immune response (B cell and T cell response) and protection against hepatitis B in the mouse model. The vaccine platform is based on virus-like particles (VLPs) of the hepatitis B virus. The VLPs ...

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Approved medications – new role in combating infections?

07-Jun-2019

Influenza A viruses periodically cause severe influenza epidemics. Due to their genetic variability, new subtypes can emerge that are no longer covered by seasonal influenza vaccines. Looking for an effective treatment of such serious influenza infections, researchers of the Paul-Ehrlich-Institut ...

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Machine Learning to increase biotechnology-based protein production

21-May-2019

In a research co-operation, researchers of the Paul-Ehrlich-Institut (PEI) have developed a mathematical model which allows more accurate forecasts and improved output in the biotechnology-based protein synthesis in host organism. The new method offers many and varied applications in ...

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Important host protein revealed for measles, mumps, and HRSV infections

16-May-2019

One approach in developing new medicines to treat virus infections is to search for components of the host cell which viruses require to enter the cell and replicate. In an international research collaboration, scientists at the Paul-Ehrlich-Institut discovered that ABCE1, a member of the ABC ...

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Raman spectroscopy allows fast analysis of vaccines

08-Oct-2018

Vaccines are complex biomedicines composed of a number of different molecules. In the manufacturing process and before marketing authorisation, extensive research is required to verify the identity, quality, efficacy and safety of the products. Fast, cost-effective yet reliable analytical methods ...

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Autoimmune disorders and regulatory B cells – marker identified

30-Jan-2018

Autoimmune disorders such as rheumatism or type 1 diabetes are on the increase world-wide. Regulatory immune cells protect healthy individuals from the disorders and combat disease progression in affected individuals. So far, little is known about the group of regulatory B cells which play a role ...

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