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Frederick W. Alt and David G. Schatz to be awarded the 2023 Paul Ehrlich and Ludwig Darmstaedter Prize

Laureates raised knowledge of the development of the immune system to a new level

20-Sep-2022

Immunologists Frederick W. Alt (73) of Harvard Medical School and David G. Schatz (64) of Yale School of Medicine are to receive the 2023 Paul Ehrlich and Ludwig Darmstaedter Prize, as the Scientific Council of the Paul Ehrlich Foundation announced. The two researchers are being acknowledged for ...

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How do killer T cells know where danger is coming from?

Road signs for immune defence cells - Study generates insights into the inner workings of the adaptive immune response

17-Aug-2022

How do killer T cells recognise cells in the body that have been infected by viruses? Matter foreign to the body is presented on the surface of these cells as antigens that act as a kind of road sign. A network of accessory proteins – the chaperones – ensure that this sign retains its stability ...

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Laboratory study: effect of antibodies against omicron variants BA.1 and BA.2 wears off quickly

26-Jul-2022

The omicron variants BA.1 and BA.2 of the SARS-CoV-2 virus, which are dominant from about December to April, can undermine the protection against infection offered by vaccinations or survived infections after only three months. This is shown by a study from Frankfurt under the leadership of the ...

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How bacteria adhere to cells: Basis for the development of a new class of antibiotics

04-Jul-2022

The adhesion of bacteria to host cells is always the first and one of the decisivesteps in the development of infectious diseases. The purpose of this adhesion by infectious pathogens is first to colonize the host organism (i.e., the human body), and then to trigger an infection, which in the ...

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New biobattery for hydrogen storage

Microbiologists has succeeded in using bacteria for the controlled storage and release of hydrogen

27-May-2022

The fight against climate change is making the search for carbon-neutral energy sources increasingly urgent. Green hydrogen, which is produced from water with the help of renewable energies such as wind or solar power, is one of the solutions on which hopes are pinned. However, transporting and ...

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Achilles’ heel of dangerous hospital pathogen discovered

Structural analysis revealed weak spots

06-Apr-2022

A team from Research Unit 2251 of the German Research Foundation led by Goethe University has shed light on the structure of an enzyme important in the metabolism of the pathogenic bacterium Acinetobacter baumannii. The enzyme “MtlD” is critical for the bacterium’s synthesis of the sugar alcohol ...

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Green chemistry needs more green toxicology

Sustainable bioeconomy: Development of environmentally friendly bio-shampoos and plant protection agent technologies

16-Feb-2022

With the early assessment of sustainable, newly developed chemicals and products it is possible to assess a potential risk of toxic substances being released at a later point in product cascades. This has been revealed in a proof-of-concept study jointly coordinated by Goethe University Frankfurt ...

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By capsule through the bloodstream

How intestinal bacteria communicate with the body

11-Nov-2021

Bacteria in the intestine pack a wide spectrum of their biomolecules into small capsules. These are transported via the bloodstream to various organs in the body and even absorbed and processed by nerve cells in the brain. This has now been shown for the first time by a team of researchers from ...

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The Paul Ehrlich and Ludwig Darmstaedter Prize 2022 will be awarded to Katalin Karikó, Özlem Türeci and Uğur Şahin

The three award winners are being honoured for their achievements in the development of mRNA for preventive and therapeutic purposes

21-Sep-2021

Katalin Karikó, Özlem Türeci, and Uğur Şahin have established a technology platform that is likely to initiate a paradigm shift in some areas of medicine - away from the external application of immunising antigens or therapeutically effective proteins to their internal production within the cells ...

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New substance classes for nanomaterials

Nano spheres and diamond slivers made of silicon and germanium

09-Sep-2021

Chemists at Goethe University Frankfurt have developed two new classes of materials in the field of nanomaterials and investigated them together with their cooperation partners at the University of Bonn: for the first time, they have succeeded in producing a nano sphere of silicon atoms and a ...

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