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Coronavirus data analysis
Open source platform enables the free and transparent overview of COVID-19 genome informations
28-Feb-2020
Dr. Wolfgang Maier and Dr. Björn Grüning from the University of Freiburg, together with researchers from universities in Belgium, Australia and the USA, have reviewed the previously available data on sequences of the novel coronavirus and published their analyses on the open source platform ...
Social control among immune cells improves defence against infections
This mechanism could improve immune therapies for cancer
13-Feb-2020
A simple mechanism, previously known from bacteria, ensures that the immune system strikes a balance between the rapid expansion of immune cells and the prevention of an excessive self-damaging reaction after an infection. This has now been deciphered by scientists at the University of Freiburg - ...
Sweet Nanoparticles trick Kidney
Researchers engineer tiny particles with sugar molecules to prevent side effect in cancer therapy
06-Feb-2020
In the past decade nanomedicine has contributed to better detection and treatment of cancer. Nanoparticles are several 100 times smaller than the smallest grain of sand and can therefore easily travel in the blood stream to reach the tumor. However, they are still too big to be removed by the ...
How the immune system becomes blind to cancer cells
04-Feb-2020
T cells play a huge role in our immune system's fight against modified cells in the body that can develop into cancer. Phagocytes and B cells identify changes in these cells and activate the T cells, which then start a full-blown program of destruction. This functions well in many cases - unless ...
Bacterial Protein Impairs Important Cellular Processes
Researchers have discovered a new function of antibiotic resistant bacteria
19-Nov-2019
Areas of skin that have been damaged by an injury are ideal niches for the concentration of Pseudomonas aeruginosa, a bacterium which impairs the healing process in tissue and creates favorable conditions for infections. Because of its resistance to most available antibiotics, this bacterium is ...
A question of time
How the immune system distinguishes between self molecules and non-self molecules such as those from pathogens
06-May-2019
A team led by the Freiburg biologists Prof. Dr. Wolfgang Schamel and Prof. Dr. Wilfried Weber conducted an experiment in which they controlled the duration of the interaction of a specific protein with T cells, a type of white blood cells, thereby showing how the immune system differentiates ...
Traffic control of cells
Researchers develop a hydrogel whose stiffness and permeability to cells can be controlled with light
27-Mar-2019
Cells in the human body can display remarkable differences in their behaviour depending on the mechanical properties of the tissue surrounding them. This is especially true for immune cells, which migrate through the body and are thus constantly exposed to tissues with different properties and ...
Stem Cells Regulate Their Fate by Altering Their Stiffness
Doing More with Less
16-Jan-2019
In adults, mesenchymal stems cells (MSCs) are primarily found in bone marrow and they play a vital role in repair of damaged organs. The transformation of a single MSC into complex tissue like cartilage and bone starts with its association with other MSCs in order to form microscopic clusters via ...
Measuring the Nanoworld
Researchers establish a benchmark for accurate determination of internal dimensions within individual molecules
05-Sep-2018
A worldwide study involving 20 laboratories has established and standardized a method to measure exact distances within individual biomolecules, down to the scale of one millionth of the width of a human hair. The new method represents a major improvement of a technology called single-molecule ...
Tiny Helpers that Clean Cells
Proteins that assist the natural recycling process in the body
15-Aug-2018
Cells collect, decompose and recycle surplus or damaged cell material. This process, known as autophagy, is important, because cellular waste can be harmful to the entire organism if it accumulates in the cells. Like the treatment of household waste, autophagy requires certain mechanisms and ...
q&more – the networking platform for quality excellence in lab and process
The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.
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