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A Pair of RNA Scissors with Many Functions

Arming CRISPR/Cas systems with an enzyme that also controls the translation of genetic information into protein

08-Feb-2018

CRISPR/Cas systems are known as promising “gene scissors” in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA – and perhaps they can even be used to correct genetic defects. A team of scientists led by Juliane Behler and Prof. Dr. Wolfgang Hess ...

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Opening the cavity floodgates

Biochemists investigate the transport of large proteins through bacterial cell membranes

25-Jan-2018

Every cell is surrounded by a membrane, which ensures the internal biochemical milieu and regulates the exchange of substances with its surroundings. In every cell membrane, there are a large number of transporters that allow only one sort of molecule to pass through. In the case of very small ...

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Personalize your medication dosages

Initial clinical tests show that biosensors could pave the way for a personalized antibiotherapy in the future

18-Jul-2017

Personalized drug therapy, adjusting the dose, dosage intervals, and the duration of treatment to fit individual patients' needs, are getting more and more important. Frequently, medications are dosed in such a way that each patient receives the same standardized amount of a certain drug. ...

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No sugar coating, but sweet nonetheless

First long-term stabile brain implant developed based on an anti-inflammatory coating

07-Apr-2017

Complex neurotechnological devices are required to directly select and influence brain waves inside the skull’s interior. Although it has become relatively easy to implement the devices, researchers are still faced with challenges when trying to keep them running properly in living organisms over ...

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Personalized antibiotic treatment

16-Nov-2016

Researchers from Freiburg have developed a sensor platform that quantifies antibiotics in human blood within minutes A team of researchers from the University of Freiburg has developed a system inspired by biology that can detect several different antibiotics in human blood or other fluids at ...

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Soft Probing with Optical Tweezers

Researchers have developed a method for measuring soft, structured surfaces using optical forces

13-Oct-2015

Surfaces separate outside from inside, control chemical reactions, and regulate the exchange of light, heat, and moisture. They thus play a special role in nature and technology. In the journal Nature Nanotechnology, the Freiburg physicist Prof. Dr. Alexander Rohrbach and his former PhD candidate ...

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New protein found in immune cells

09-Oct-2015

Researchers of the University of Freiburg have discovered Kidins220/ARMS in B cells. They also determined that it plays a decisive role in the production of antibodies and the formation of B cells, which are a type of white blood cells. Various teams of researchers had already found that ...

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Thousands of Droplets for Diagnostics

Researchers develop new method enabling DNA molecules to be counted in just 30 minutes

29-Jun-2015

A team of scientists including PhD student Friedrich Schuler from the Laboratory of MEMS Applications at the Department of Microsystems Engineering (IMTEK) of the University of Freiburg has developed a method for dividing a DNA sample into thousands of tiny droplets. What sets it apart from ...

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Building Scaffolds in the Cell’s Power Stations

Researchers at the University of Freiburg discover a basic architectural principle of mitochondria

08-May-2015

A group of scientists led by Assistant Professor Dr. Martin van der Laan has decoded the molecular basis for the characteristic structures inside of mitochondria. Mitochondria are the powerhouses of cells and contain microscopic, strongly infolded membrane structures. These structures allow ...

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