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The attachment of the small protein ubiquitin to other proteins regulates numerous biological processes, including signal transduction and metabolism
Scientists have discovered that the protein ubiquitin plays an important role in the regulation of the aging process. Ubiquitin was previously known to control numerous processes, such as signal transduction and metabolism. Prof. Dr. David Vilchez and his colleagues at the CECAD Cluster of ...
Protein balance in sex cells influences protein accumulation in other tissues through specific signaling
A recent study shows that a healthy reproductive system can prevent disease-related protein accumulation in distant tissues, such as neurons, and alteration of mitochondria - the power plants of cells. An imbalance of proteins, for example a build-up of damaged proteins in brain cells, can lead ...
An international research team has developed a model that predicts growth rates and resistance mechanisms of common bacterial mutants at different drug doses
A team of scientists from the University of Cologne (Germany) and the University of Uppsala (Sweden) has created a model that can describe and predict the evolution of antibiotic resistance in bacteria. Resistance to antibiotics evolves through a variety of mechanisms. A central and still ...
Findings will help catalyst research take an important step forward
“Titanium silicalite-1” (TS-1) is not a new catalyst: It has been almost 40 years since its development and the discovery of its ability to convert propylene into propylene oxide, an important basic chemical in the chemical industry. Now, by combining various methods, a team of scientists from ...
Molecular repair pathway for cellular energy production found
If the energy supply of a cell is disturbed by damage, it can protect itself from functional losses and repair itself in a kind of workshop mode. That is the result of a new study conducted by molecular biologist Professor Dr. Aleksandra Trifunovic and Dr. Karolina Szcepanowska as a leading ...
The smell of food affects physiology and aging. That is the result of research conducted on the model organism of the roundworm by a research team led by Professor Thorsten Hoppe at the Cluster of Excellence for Aging Research (CECAD). Surprisingly, this relationship is due to a single pair of ...
New therapies possible in the long run
The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne’s Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington’s disease. Particularly, they identified a system ...
Researchers uncover the link between protein aggregation and aging
Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation ...
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