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Protein Spheres Protect the Genome of Cancer Cells

Hollow spheres made of MYC proteins open new doors in cancer research: Researchers start a company

28-Nov-2022

MYC genes and their proteins play a central role in the emergence and development of almost all cancers. They drive the uncontrolled growth and altered metabolism of tumour cells. And they help tumours hide from the immune system. MYC proteins also show an activity that was previously unknown – ...

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Gene activity in a test tube

An accurate picture of gene activity can provide the key to the development of new, targeted therapies

18-Oct-2022

When searching for the causes of illnesses and developing new treatments, it is absolutely vital to have a precise understanding of the genetic fundamentals. Würzburg researchers have devised a new technique for this purpose. Pathological processes are usually characterised by altered gene ...

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Artificial Enzyme Splits Water

Progress has been made on the path to sunlight-driven production of hydrogen

05-Oct-2022

Chemists from Würzburg present a new enzyme-like molecular catalyst for water oxidation. Mankind is facing a central challenge: it must manage the transition to a sustainable and carbon dioxide-neutral energy economy. Hydrogen is considered a promising alternative to fossil fuels. It can be ...

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New Players in the Immune Response

This discovery has consequences – for vaccination strategies as well as for immunotherapies against cancer

25-Aug-2022

Lymph nodes trigger very different immune responses – depending on which body tissue they are connected to. Special T cells are responsible for this newly discovered relation. The human body contains 600 to 800 lymph nodes, which are specialised organs that trigger immune responses. To be ...

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How sugar promotes inflammation

Excessive sugar consumption can promote inflammatory processes in the body and facilitate the development of autoimmune diseases.

24-Mar-2022

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease. In affected patients, the immune system attacks the body's own tissue and the consequences are, for example, chronic inflammatory bowel diseases such ...

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A boost for CRISPR research

PAM-DETECT enables faster characterisation of CRISPR immune systems

28-Feb-2022

For many diseases, the tools of medicine are reaching their limits. CRISPR technologies open new avenues for diagnostics and therapies, although the natural source of CRISPR remains largely untapped. Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a ...

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Columns Designed from Nanographenes

Several layers of nanographenes stacked on top of each other: such functional elements could one day be used in solar cells

09-Feb-2022

Graphene is a carbon material that forms extremely thin layers. Because of its unusual properties, it is interesting for many technical applications. This also applies to polycyclic aromatic hydrocarbons (PAHs), which can be regarded as cut-outs of graphene. They are considered promising ...

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How Poxviruses Multiply

For the first time, the polymerase of vaccinia viruses observed at work at the atomic level

27-Sep-2021

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. For the first time, scientists of the University of Würzburg's Biocenter have been able to gain atomic-level insights into the functioning of the molecular machinery involved in the process. The ...

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Obstacles on the racetrack of life

New picture of the transcription

19-Jul-2021

mRNA plays a key role in the conversion of genetic information from DNA to proteins. Their production is a delicate process. A research team at the University of Würzburg has now identified a crucial factor. The corona pandemic has ensured that the term "mRNA" is now also known to a large public ...

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Anti-tumor agent from the intestine

Certain metabolites of bacteria from the intestine make immune cells more aggressive: The findings could help improve cancer therapies

14-Jul-2021

It is believed to be involved in the development of chronic inflammatory intestinal diseases, to trigger diabetes, to be responsible for obesity, even neurological diseases such as multiple sclerosis and Parkinson's could have their causes here – not to mention depressions and autistic disorders. ...

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