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Perturbation-free studies of single molecules

New applications in the fields of quantum science, spectroscopy and chemistry

16-Mar-2020

Researchers of the University of Basel have developed a new method with which individual isolated molecules can be studied precisely – without destroying the molecule or even influencing its quantum state. This highly sensitive technique for probing molecules is widely applicable and paves the ...

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Virtual screening for active substances against the coronavirus

11-Mar-2020

The University of Basel is part of the global search for a drug to fight the rampant coronavirus. Researchers in the Computational Pharmacy group have so far virtually tested almost 700 million substances, targeting a specific site on the virus – with the aim of inhibiting its multiplication. Due ...

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Inner “clockwork” sets the time for cell division in bacteria

12-Feb-2020

Researchers at the Biozentrum of the University of Basel have discovered a “clockwork” mechanism that controls cell division in bacteria. In two publications, in “Nature Communications” und “PNAS”, they report how a small signaling molecule starts the “clock”, which informs the cell about the ...

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Kiss and run: How cells sort and recycle their components

30-Jan-2020

What can be reused and what can be disposed of? Cells also face this tricky task. Researchers from the Biozentrum of the University of Basel have now discovered a cellular machine, called FERARI, that sorts out usable proteins for recycling. In Nature Cell Biology, they explain how FERARI works ...

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Nanocontainers introduced into the nucleus of living cells

29-Jan-2020

An interdisciplinary team from the University of Basel has succeeded in creating a direct path for artificial nanocontainers to enter into the nucleus of living cells. To this end, they produced biocompatible polymer vesicles that can pass through the pores that decorate the membrane of the cell ...

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2D materials: arrangement of atoms measured in silicene

03-Jan-2020

Silicene consists of a single layer of silicon atoms. In contrast to the ultra-flat material graphene, which is made of carbon, silicene shows surface irregularities that influence its electronic properties. Now, physicists from the University of Basel have been able to precisely determine this ...

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Novel combination of antibodies leads to significant improvement in cancer immunotherapy

02-Jan-2020

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demonstrated by a study in animal models by medical oncologists and scientists at the University of Basel that has been published in the scientific journal ...

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Molecular bodyguards against Parkinson’s disease

06-Dec-2019

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson’s disease. A disturbed relationship to these “bodyguards” leads to cell damage and the formation of Lewy bodies typical for Parkinson’s disease. Parkinson’s disease is ...

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How to control friction in topological insulators

16-Oct-2019

Topological insulators are innovative materials that conduct electricity on the surface, but act as insulators on the inside. Physicists at the University of Basel and the Istanbul Technical University have begun investigating how they react to friction. Their experiment shows that the heat ...

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Too much of a good thing: overactive immune cells trigger inflammation

20-Sep-2019

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. This cellular metabolic overactivity leads to inflammation, as an international research team ...

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