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2D materials: arrangement of atoms measured in silicene

03-Jan-2020

Silicene consists of a single layer of silicon atoms. In contrast to the ultra-flat material graphene, which is made of carbon, silicene shows surface irregularities that influence its electronic properties. Now, physicists from the University of Basel have been able to precisely determine this ...

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Novel combination of antibodies leads to significant improvement in cancer immunotherapy

02-Jan-2020

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demonstrated by a study in animal models by medical oncologists and scientists at the University of Basel that has been published in the scientific journal ...

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Molecular bodyguards against Parkinson’s disease

06-Dec-2019

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson’s disease. A disturbed relationship to these “bodyguards” leads to cell damage and the formation of Lewy bodies typical for Parkinson’s disease. Parkinson’s disease is ...

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How to control friction in topological insulators

16-Oct-2019

Topological insulators are innovative materials that conduct electricity on the surface, but act as insulators on the inside. Physicists at the University of Basel and the Istanbul Technical University have begun investigating how they react to friction. Their experiment shows that the heat ...

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Too much of a good thing: overactive immune cells trigger inflammation

20-Sep-2019

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. This cellular metabolic overactivity leads to inflammation, as an international research team ...

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Unique fingerprint: What makes nerve cells unmistakable?

12-Sep-2019

Protein variations that result from the process of alternative splicing control the identity and function of nerve cells in the brain. This allows organisms to build a highly complex neuronal network with only a limited number of genes. The study describing a detailed map of neuronal splicing ...

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Silicon as a semiconductor: silicon carbide would be much more efficient

09-Sep-2019

In power electronics, semiconductors are based on the element silicon – but the energy efficiency of silicon carbide would be much higher. Physicists of the University of Basel, the Paul Scherrer Institute and ABB explain what exactly is preventing the use of this combination of silicon and ...

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Signal blocks stem cell division in the geriatric brain

30-Aug-2019

Scientists from Basel have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation. According to the researchers, the gene regulator Id4 controls whether stem cells remain in a state of rest or enter cell division. The results ...

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Making cancer stem cells visible to the immune system

New results may enable innovative treatment concept against leukemia

19-Jul-2019

Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. This protective mechanism can be tricked with drugs. In the journal "Nature", scientists from Basel, Tübingen and Heidelberg describe the new therapeutic approaches that can ...

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Speed controllers for protein production

15-Jul-2019

The translation of the genetic code into proteins is a vital process in any cell. Prof. Mihaela Zavolan’s team at the Biozentrum, University of Basel, has now uncovered important factors that influence the speed of protein synthesis in the cell. The results, recently published in “PNAS”, serve as ...

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