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15 Current news of Universität Bonn

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New method allows precise gene control by light

Study enhances research toolbox with a new tool with great potential

02-Oct-2020

A novel optical switch makes it possible to precisely control the lifespan of genetic "copies". These are used by the cell as building instructions for the production of proteins. The method was developed by researchers from the universities of Bonn and Bayreuth. It may significantly advance the ...

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A "corset" for the enzyme structure

Structure of biocatalysts depends on whether they are in cells or in the test tube

29-Apr-2020

The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable "hinges". The shape of enzymes can depend on whether their structure is measured in the test ...

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How cells recognize uninvited guests

16-Apr-2020

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders. The enzymes RNaseT2 and RNase2 cut ribonucleic acids (RNAs) of bacteria ...

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Activation of opioid receptor uncovered

29-Nov-2019

Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new active substances. The opioids used today to treat severe pain can be ...

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Epilepsy: Function of "brake cells" disrupted

04-Oct-2019

In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn, in which ...

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How Artificial Intelligence Detects Rare Diseases

11-Jun-2019

Every year, around half a million children worldwide are born with a rare hereditary disease. Obtaining a definitive diagnosis can be difficult and time consuming. In a study of 679 patients with 105 different rare diseases, scientists from the University of Bonn and the Charité - ...

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Cell editors correct genetic errors

Study improves understanding of a widespread mechanism

05-Mar-2019

Almost all land plants employ an army of editors who correct errors in their genetic information. Researchers at the University of Bonn have now transferred parts of this machinery into a bacterium. Their results confirm a controversial thesis on the functioning of this widespread mechanism. One ...

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Tiny nanomachine successfully completes test drive

11-Apr-2018

Together with colleagues from the USA, scientists from the University of Bonn and the research institute Caesar in Bonn have used nanostructures to construct a tiny machine that constitutes a rotatory motor and can move in a specific direction. The researchers used circular structures from ...

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New mouse model makes stem cells light up green

Random find opens up new perspectives

06-Feb-2018

Multipotent stromal cells have long been a hot topic in medical research. Scientists at the University of Bonn have now found a way to specifically mark these stem cells. This makes it possible to analyze their distribution pattern and their function in living organisms. In order to examine a ...

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The protein “CHIP” unfurls anti-aging activity

Researchers uncover the link between protein aggregation and aging

24-Apr-2017

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation ...

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