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New group of antibacterial molecules identified

International research group discovers promising scaffold for antimicrobial agents

19-Nov-2021

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria. Since the properties of the molecules can easily be altered chemically, the hope is to develop ...

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Epigenetics: Immunisation is passed on to offspring

22-Oct-2021

Does an infection also affect the immunisation of subsequent generations? Researchers at Radboud University (Netherlands) have investigated this together with the Universities of Bonn, Saarland, Lausanne (Switzerland) and Athens (Greece). Mouse sires that had previously overcome infection with ...

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Immune cells in the brain share the work

This cooperation is impaired in mutations that can cause Parkinson's disease

24-Sep-2021

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE) and the Institut François Jacob in France. However, in certain ...

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Persistent dysfunction in natural killer cells has been implicated in severe COVID-19 progressions

14-Sep-2021

Based on previous studies of the COVID-19 pandemic, it is known that a specific form of white immune cells, natural killer (NK) cells, make an important contribution to the early antiviral immune response against SARS-CoV-2. An international team led by the University of Bonn has now found that ...

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New substance classes for nanomaterials

Nano spheres and diamond slivers made of silicon and germanium

09-Sep-2021

Chemists at Goethe University Frankfurt have developed two new classes of materials in the field of nanomaterials and investigated them together with their cooperation partners at the University of Bonn: for the first time, they have succeeded in producing a nano sphere of silicon atoms and a ...

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Novel method for fast 3D microscopy

03-Aug-2021

Researchers at the ImmunoSensation2 Cluster of Excellence at the University of Bonn, the University Hospital and the research center caesar have develop a method that allows using multi-focal images to reconstruct the movement of fast biological processes in 3D. In the past, many discoveries ...

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Researchers investigate structural changes in snap-frozen proteins

A novel method allows visualization of molecular motions lasting a few millionths of a second

03-May-2021

Researchers at the University of Bonn and the research center caesar have succeeded in ultra-fast freezing proteins after a precisely defined period of time. They were able to follow structural changes on the microsecond time scale and with sub-nanometer precision. Owing to its high spatial and ...

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COVID-19 has multiple faces

Scientists present latest findings on the coronavirus

20-Jan-2021

According to current studies, the COVID-19 disease which is caused by the SARS-CoV-2 coronavirus comprises at least five different variants. These differ in how the immune system responds to the infection. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the University ...

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Customized programming of human stem cells

The results open new possibilities in research

02-Dec-2020

Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues. However, the "recipes" for this conversion are often complicated and difficult to implement. Researchers at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden, Harvard ...

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Genetic disposition protects immune system from aging

Study reveals a previously unknown function of a human gene

11-Nov-2020

A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system. This is shown by a recent study led by the University of Bonn. When the gene is not active enough, the immune defense system undergoes characteristic ...

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