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17 Current news of Universität Bonn
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Customized programming of human stem cells
The results open new possibilities in research
02-Dec-2020
Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues. However, the "recipes" for this conversion are often complicated and difficult to implement. Researchers at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden, Harvard ...
Genetic disposition protects immune system from aging
Study reveals a previously unknown function of a human gene
11-Nov-2020
A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system. This is shown by a recent study led by the University of Bonn. When the gene is not active enough, the immune defense system undergoes characteristic ...
New method allows precise gene control by light
Study enhances research toolbox with a new tool with great potential
02-Oct-2020
A novel optical switch makes it possible to precisely control the lifespan of genetic "copies". These are used by the cell as building instructions for the production of proteins. The method was developed by researchers from the universities of Bonn and Bayreuth. It may significantly advance the ...
A "corset" for the enzyme structure
Structure of biocatalysts depends on whether they are in cells or in the test tube
29-Apr-2020
The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable "hinges". The shape of enzymes can depend on whether their structure is measured in the test ...
How cells recognize uninvited guests
16-Apr-2020
Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders. The enzymes RNaseT2 and RNase2 cut ribonucleic acids (RNAs) of bacteria ...
Activation of opioid receptor uncovered
29-Nov-2019
Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new active substances. The opioids used today to treat severe pain can be ...
Epilepsy: Function of "brake cells" disrupted
04-Oct-2019
In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn, in which ...
How Artificial Intelligence Detects Rare Diseases
11-Jun-2019
Every year, around half a million children worldwide are born with a rare hereditary disease. Obtaining a definitive diagnosis can be difficult and time consuming. In a study of 679 patients with 105 different rare diseases, scientists from the University of Bonn and the Charité - ...
Cell editors correct genetic errors
Study improves understanding of a widespread mechanism
05-Mar-2019
Almost all land plants employ an army of editors who correct errors in their genetic information. Researchers at the University of Bonn have now transferred parts of this machinery into a bacterium. Their results confirm a controversial thesis on the functioning of this widespread mechanism. One ...
Tiny nanomachine successfully completes test drive
11-Apr-2018
Together with colleagues from the USA, scientists from the University of Bonn and the research institute Caesar in Bonn have used nanostructures to construct a tiny machine that constitutes a rotatory motor and can move in a specific direction. The researchers used circular structures from ...
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