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How to separate nanoparticles by “shape”

New strategy to separate molecules

13-Jun-2019

In our daily lives, the purpose and function of an item is defined by either its material, e.g. a rain jacket is fabricated of water-proof material, or its shape, e.g. a wheel is round to enable a rolling motion. What is the impact of the two factors on the nanoscale? The impact of material, ...

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When changing one atom makes molecules better

A method to replace hydrogen with fluorine in organic molecules makes drugs more effective

07-Mar-2019

The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease. Organic synthesis is the field that enables these developments as it offers the toolbox to diversify chemical structures. The group of Nuno Maulide, recently named the Scientist ...

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RNA Microchips

A new chapter in ribonucleic acid synthesis

08-Nov-2018

Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. In the “RNA world” hypothesis, RNA is able to support life on its own because it can both store information and catalyze biochemical ...

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Nanocages in the lab and in the computer

How DNA-based dendrimers transport nanoparticles

22-Oct-2018

How to create nanocages, i.e., robust and stable objects with regular voids and tunable properties? Short segments of DNA molecules are perfect candidates for the controllable design of novel complex structures. Physicists from the University of Vienna, the Technical University of Vienna, the ...

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When sulfur disappears without trace

Chemists finally find a surprisingly simple reaction to make a family of bioactive molecules

20-Aug-2018

Many natural products and drugs feature a so-called dicarbonyl motif – in certain cases however their preparation poses a challange to organic chemists. In their most recent work, Nuno Maulide and his coworkers from the University of Vienna present a new route for these molecules. They use ...

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Artificial intelligence for obtaining chemical fingerprints

Neural networks carry out chemical simulations in record time

28-Sep-2017

Researchers at the Universities of Vienna and Göttingen have succeeded in developing a method for predicting molecular infrared spectra based on artificial intelligence. These chemical "fingerprints" could only be simulated by common prediction techniques for small molecules in high quality. With ...

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Bacteria stab amoebae with daggers

22-Aug-2017

Researchers from ETH Zurich and the University of Vienna have discovered a type of bacteria that uses tiny daggers to prevent itself from being eaten by amoebae. The scientists also resolved the three-dimensional structure of the mechanism that allows the micro-daggers to be shot ...

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When protein crystals grow

Chemists are investigating a substance class for biological and pharmaceutical applications

06-Jan-2017

Annette Rompel and her team of the Department of Biophysical Chemistry at the University of Vienna are investigating so-called polyoxometalates. These compounds exhibit a great diversity and offer the scientists a wide range of applications. In interaction with enzymes they can enable the ...

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The marine super glue

Mega-strong and very mobile

09-Aug-2016

Barnacles exude an adhesive with exceptional bonding properties. In a project supported by the Austrian Science Fund FWF, biologists from Vienna have investigated this substance which has enormous medical and engineering potential and have thereby gained many new insights. It was a typical case ...

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Unraveling a truly one-dimensional carbon solid

Researchers present a direct first proof of stable ultra-long 1D carbon chains

06-Apr-2016

Elemental carbon appears in many different modifications, including diamond, fullerenes and graphene. Their unique structural, electronic, mechanical, transport and optical properties have a broad range of applications in physics, chemistry and materials science, including composite materials, ...

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