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How do killer T cells know where danger is coming from?

Road signs for immune defence cells - Study generates insights into the inner workings of the adaptive immune response

17-Aug-2022

How do killer T cells recognise cells in the body that have been infected by viruses? Matter foreign to the body is presented on the surface of these cells as antigens that act as a kind of road sign. A network of accessory proteins – the chaperones – ensure that this sign retains its stability ...

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OSCAR detects cells in standby mode

New tool to better understand the biology of dormant stem cells

24-Jun-2021

Dormancy is a sleep-like state of cells that protects them from genetic damage and thus prolongs their survival. This state is reversible and characterized by low metabolic activity and division rate. Researchers from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) and the ...

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New kind of interaction discovered in hydrogen-producing enzymes

The findings should help to develop more efficient miniaturised hydrogenase catalysts in the future

18-Aug-2020

In hydrogenase enzymes, the transports of protons and electrons have been considered to be separate events until now. However, coupling is the key to success here. Hydrogenases can convert hydrogen just as efficiently as expensive platinum catalysts. In order to make them usable for ...

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Shaping the social networks of neurons

Identification of a protein complex that attracts or repels nerve cells during development

28-Jan-2020

The three proteins Teneurin, Latrophilin and FLRT hold together and bring neighboring neurons into close contact, enabling the formation of synapses and the exchange of information between the cells. In the early phase of brain development, however, the interaction of the same proteins leads to ...

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A new method for the 3-D printing of living tissues

21-Aug-2017

Scientists at the University of Oxford have developed a new method to 3D-print laboratory-grown cells to form living structures. The approach could revolutionise regenerative medicine, enabling the production of complex tissues and cartilage that would potentially support, repair or augment ...

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How can engineers make steel that doesn't baulk at hydrogen?

16-Nov-2015

For over 100 years engineers have known that hydrogen can cause metals to become incredibly brittle, but they've been able to do little to protect against it. Now, Oxford University researchers are working on a large collaborative project to build the metals of the future, that can retain their ...

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For faster, larger graphene add a liquid layer

16-Jul-2015

Millimetre-sized crystals of high-quality graphene can be made in minutes instead of hours using a new scalable technique, Oxford University researchers have demonstrated. In just 15 minutes the method can produce large graphene crystals around 2-3 millimetres in size that it would take up to 19 ...

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