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Designed antiviral proteins inhibit SARS-CoV-2 in the lab

Computer-designed, synthetic miniproteins act as potent, stable antivirals that block coronavirus infection of cultured human cells

14-Sep-2020

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. In the experiments, the lead antiviral candidate, named LCB1, rivaled the best-known SARS-CoV-2 neutralizing antibodies in its protective actions. LCB1 is ...

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New 'molecular computers' find the right cells

A laboratory breakthrough in cell targeting may improve the safety of cancer-killing CAR T cells

26-Aug-2020

Scientists have demonstrated a new way to precisely target cells by distinguishing them from neighboring cells that look quite similar. Even cells that become cancerous may differ from their healthy neighbors in only a few subtle ways. A central challenge in the treatment of cancer and many other ...

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Deep-sea anglerfishes have evolved a new type of immune system

The discovery points to possible new ways of improving immune defence in patients who suffer from the consequences of a immune disabilities

03-Aug-2020

Deep-sea anglerfishes have evolved a curious reproductive strategy. Tiny males attach themselves to gigantic females so tightly that the tissues of the two animals eventually fuse. The male esssentially turns into a sperm-producing parasite. This phenomenon is known as sexual parasitism which ...

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Progress toward Personalized Medicine

Microfluidic chip for analysis of single cells

21-Aug-2018

A few little cells that are different from the rest can have a big effect. For example, individual cancer cells may be resistant to a specific chemotherapy—causing a relapse in a patient who would otherwise be cured. In the journal Angewandte Chemie, scientists have now introduced a ...

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Toilet paper sensors

Tissue paper sensors show promise for health care, entertainment, robotics

16-Feb-2018

University of Washington engineers have turned tissue paper – similar to toilet tissue – into a new kind of wearable sensor that can detect a pulse, a blink of an eye and other human movement. The sensor is light, flexible and inexpensive, with potential applications in health care, entertainment ...

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Team refrigerates liquids with a laser for the first time

18-Nov-2015

Since the first laser was invented in 1960, they've always given off heat -- either as a useful tool, a byproduct or a fictional way to vanquish intergalactic enemies. But those concentrated beams of light have never been able to cool liquids. University of Washington researchers are the first to ...

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