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Help for stressed-out cells in a crisis

Biologists discover a new function of mitochondria as the "patron saints" of protein folding

31-Jan-2022

According to a team of researchers at the University of Münster, mitochondria provide unexpected help for cells in a crisis by respiring away harmful substances. A current study produced by the Institute of Biology and Biotechnology of Plants (IBBP) shows three things: that this mechanism can be ...

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"Hand in hand in hand": three catalysts solve chemical problem

Research team develops new strategy to create molecular compounds without multi-step syntheses

14-Jan-2022

For organic synthesis, i.e. for the production of carbon-based compounds, it is important to develop synthesis processes by which the desired product can be obtained in good yield. At the same time, the processes should be sustainable: for example, they should use environmentally friendly and ...

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Chemists succeed in synthesis of aminoalcohols by utilizing light

New method for generating the least accessible form of vicinal aminoalcohols

06-Jan-2021

Whether in beta-blockers to treat high blood pressure or in natural products: So-called vicinal aminoalcohols are high-quality organic compounds that are found in many everyday products. However, their production is difficult. For a long time, chemists are trying to develop efficient methods of ...

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Understanding the progress of viral infections

Viral expression model created that can be used to simulate and analyse a large number of viral infections – including the one with SARS-CoV-2

13-Oct-2020

It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans. Even decades of research have only produced a ...

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Watching changes in plant metabolism – live

Researchers use a new method of in vivo biosensor technology

17-Aug-2020

Almost all life on Earth, in particular our food and our health, depend on metabolism in plants. In order to understand how these metabolic processes function, researchers at the Institute of the Biology and Biotechnology of Plants at the University of Münster with the participation of the ...

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Long-standing problem in organic chemistry solved

Chemists develop a bioinspired strategy for the controlled synthesis of polyenes

20-Jul-2020

They occur in nature, are reactive and play a role in many biological processes: polyenes. It is no wonder that chemists have for a long time been interested in efficiently constructing these compounds – not least in order to be able to use them for future biomedical applications. However, such ...

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Researchers create a photographic film of a molecular switch

Following the motion of a light-responsive molecule

22-Jun-2020

Molecular switches – they are the molecular counterparts of electrical switches and play an important role in many processes in nature. Such molecules can reversibly interconvert between two or more states and thereby control molecular processes. In living organisms, for example, they play a role ...

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Triggered by light, a novel way to switch on an enzyme

Researchers identify enzyme which becomes catalytically active by light

28-May-2020

In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme ...

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Artificial ‘candy canes’ block viruses

Synthetic glycomimetics attach to the viruses’ binding sites, which viruses normally use to attach to sugars on the cell surface

22-Apr-2020

Synthetic chains of molecules containing different sugars can inhibit viruses effectively. The extent to which such molecules could be used as antiviral drugs is illustrated by a team of researchers from Heinrich Heine University Düsseldorf (HHU) and University of Münster (WWU) in the February ...

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Chemists allow boron atoms to migrate

Researchers present carbon-carbon couplings in which the semi-metal boron is retained

21-Jan-2020

Organic molecules with atoms of the semi-metal boron are among the most important building blocks for synthesis products that are needed to produce drugs and agricultural chemicals. However, during the usual chemical reactions used in industry, the valuable boron unit, which can replace another ...

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