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Chemists allow boron atoms to migrate
Researchers present carbon-carbon couplings in which the semi-metal boron is retained
21-Jan-2020
Organic molecules with atoms of the semi-metal boron are among the most important building blocks for synthesis products that are needed to produce drugs and agricultural chemicals. However, during the usual chemical reactions used in industry, the valuable boron unit, which can replace another ...
Two chiral catalysts working hand in hand
Chemists develop a synthetic method providing access to different stereoisomers of a molecule
05-Dec-2019
Just as our left hand is not superposable to our right hand, the mirror image of certain molecules cannot be overlapped onto it, even when turned or twisted. These two mirror images are referred to by chemists as enantiomers and the molecule is said to be chiral. Chirality, which is a word ...
Light to build biologically active compounds
Photocatalyst builds 3D scaffolds from flat aromatics
18-Nov-2019
Some of the most biologically active molecules, including synthetic drugs, contain a central, nitrogen-containing chemical structure called an isoquinuclidine. This core has a three-dimensional shape which means it has the potential to interact more favourably with enzymes and proteins than flat, ...
New insights into the evolution of proteins
23-Oct-2019
How do bacteria manage to adapt to synthetic environmental toxins and, for example, to even develop strategies for using a pesticide and chemical warfare agent as food within less than 70 years? The evolutionary adaptations underlying such processes have now been studied in detail by an ...
Chemists give chance a helping hand
Developing a method for discovering new chemical reactions
03-Jul-2019
Whether they are synthetic materials such as PET and Teflon, medicines or flavourings, life without synthetically produced compounds is barely conceivable in our everyday lives today. The chemical industry depends on efficient, long-term methods of producing synthetically derived molecules. For ...
Converting biomass by applying mechanical force
15-Mar-2019
One of the greatest global challenges is the efficient use of renewable sources in order to meet the increasing demand for energy and feedstock chemicals in the future. In this context, biomass is a promising alternative to existing fossil sources such as coal or oil. Cellulose plays a decisive ...
Genes out of thin air
Precursors of genes constantly emerge "out of thin air" – but only a few survive for good
13-Sep-2018
Accumulating evidence suggests that new genes can arise spontaneously from previously non-coding DNA instead of through the gradual mutation of established genes. Bioinformaticians at the University of Münster are now, for the first time, studying the earliest stages in the emergence of such ...
Novel method for rapid detection of antibiotic resistance
15-Feb-2018
Respiratory, urinary tract, wound infections, and sepsis: the list of sites in which severe and life-threatening diseases manifest as a result of multidrug resistant microorganisms is long. The best option is an antibiotic treatment targeted specifically to the detected pathogen. However, the ...
Chemists develope a new method for the formation of fluorinated molecular rings
Sought-after compounds readily accessible for the first time
14-Aug-2017
Dyes, pharmaceuticals, and functional materials – all of these products are generally based on innovative molecules made by chemists. For their production several chemical reactions are available to the expert, however, limitations remain. For example, fluorinated compounds, molecules that ...
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