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Hollow spheres made of MYC proteins open new doors in cancer research: Researchers start a company
MYC genes and their proteins play a central role in the emergence and development of almost all cancers. They drive the uncontrolled growth and altered metabolism of tumour cells. And they help tumours hide from the immune system. MYC proteins also show an activity that was previously unknown – ...
Some reactions in the reverse Krebs cycle can also be run under meteorite catalysis
Naturally occurring chemical reactions may have evolved into the biochemical processes we know today. A team of researchers has now discovered that a reaction sequence from the so-called reverse Krebs cycle—a fundamental biochemical process—can also take place without enzymes. The team writes in ...
Development of new antibody therapies necessary
Are the currently approved antibody therapies used to treat individuals at increased risk for severe COVID-19 disease also effective against currently circulating viral variants? A recent study by researchers at the German Primate Center (DPZ) – Leibniz Institute for Primate Research and ...
Metrics for organ development have now been defined for the first time
Researchers from Dresden and Vienna reveal link between connectivity of three-dimensional structures in tissues and the emergence of their architecture to help scientists engineer self-organising tissues that mimic human organs. Organs in the human body have complex networks of fluid-filled tubes ...
Pasta waste from the production shows excellent properties for fermentations
Almost 30% of the food produced globally is lost or wasted at some point along the food supply chain. The recent publication 'Upgrading pasta wastes through lactic acid fermentations' by the Leibniz Institute of Agricultural Engineering and Bioeconomy (ATB) and IDELUX, demonstrates the potential ...
It wasn't until 2021 that a new therapy came on the market, in the form of a class of drugs called compstatins, to inhibit harmful immune responses of the complement system
Although the complement system forms part of the innate immune system, it can cause damage to the body in some cases. This is because unwanted complement activation contributes to many autoimmune and chronic inflammatory diseases. Now, researchers have described molecular details of a recently ...
New biological tool for tracking cellular processes
The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding RNA, which is RNA that is not further converted into proteins. A research team from the Technical ...
Holes in the blood-brain barrier
Although the coronavirus known as SARS-CoV-2 does not infect nerve cells, it can cause damage to the nervous system. Researchers from the University of Basel and University Hospital Basel have studied the mechanisms responsible for this effect, known as “neuro-Covid”, and identified starting ...
Low toxicity, high efficiency: ZnSe/ZnS quantum dots as photocatalysts
Chemistry is increasingly making use of the trick plants can do with photosynthesis: driving chemical reactions that run poorly or do not occur spontaneously at all with light energy. This requires suitable photocatalysts that capture light energy and make it available for the reaction. In the ...
Clinical study on nasopharyngeal cancer with unexpected result
Patients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor. Until now, it was feared that vaccination against Covid-19 could reduce the success of cancer treatment or cause severe side effects. A recent study by the Universities of Bonn ...
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