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The search for APIs in the genome of fungi

Bioinformatics to identify essential genes for designing efficient strains

Dr. Christian Derntl

Fungi hold enormous potential to discover new active pharmaceutical ingredients (APIs) and valua-ble substances, for example antibiotics, pigments and raw materials for biological plastics. While conventional discovery methods are reaching their limits, recent developments in bioinformatics and biotechnology are paving the way for new approaches that promise the discovery of new sub-stances.

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The aim of personalized medicine (or precision medicine) is to take patients’ personal features into consideration as much as possible for their medical treatment, thereby going beyond the (…)

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The potential of single cells

The cell is the basic unit of our body – and key to understanding the biology of good health, as well as how molecular dysfunction leads to disease. Yet our understanding of the hundreds (…)

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