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The search for APIs in the genome of fungi

Bioinformatics to identify essential genes for designing efficient strains

Fungi hold enormous potential to discover new active pharmaceutical ingredients (APIs) and valua-ble substances, for example antibiotics, pigments and raw materials for biological plastics. While conventional discovery methods are reaching their limits, recent developments in bioinformatics and ...

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Protein-rich meat alternatives made from fungi

Mycoprotein as an alternative, healthy source of protein

Protein-rich “mycoprotein” is a sustainable and biological food ingredient obtained by targeted fermentation of a starter culture. Particularly its intrinsic fiber structure makes it worth investigating whether mycoprotein is suitable for producing low-processed alternatives to meat.

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Dandelions as a new source of natural rubber

Molecular breeding strategies enable the sustainable extraction and application of natural rubber from Russian dandelions

More than 12,500 plants produce latex, a colorless to white milky sap that contains, among other things, natural rubber. However, this industrially indispensable raw material is found in only three plants in a quality required to produce high-performance rubber products such as car tires.

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Microbial degradation of toxic azo dyes

Complete and hazard-free conversion of azo compounds by microorganisms

Have you ever looked around you and paid attention to the colorful products such as clothes, cosmetics, and foods that you purchase? If you wonder where all these colors come from, then you might want to know more about azo dyes.

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Vitamin D in plants

Detection and identification of vitamin D metabolites in plant sources

A vitamin is defined as an organic molecule essential for health. Indeed, vitamin D has been associated with bone health and with immune-related effects, however a vitamin D deficiency has been associated with chronic diseases and mortality [1].

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Effective drug navigation in sepsis

Cell type specific nanoparticles as carriers can bypass side effects on the immune system

Many drug candidates never reach clinical use due to their side effects. For example, inhibitors of phosphoinositide 3-kinase-γ, a signaling protein that plays an important role in infections, cannot be used because of their side effects on the immune response.

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Organs-on-a-Chip

Chip-based tissue and organ systems for personalized medicine

The aim of personalized medicine (or precision medicine) is to take patients’ personal features into consideration as much as possible for their medical treatment, thereby going beyond the functional diagnosis of the disease. A promising concept that is gaining ever more attention and showing ...

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Weighty matters for the European Pharmacopoeia

A new General Chapter addresses balances for analytical purposes

Weighing is one of the key activities carried out in every quality control (QC) laboratory. Usually it is one of the first steps in a whole analysis chain, e.g. when a sample or a standard is prepared for subsequent dilution and HPLC or qNMR analysis.

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The importance of traceability in laboratory medicine

Ensuring comparability of clinical results is important in the age of globalization

World Metrology Day is celebrated annually on the 20th of May and this year’s focus on health provides an opportunity to emphasize the importance of comparable and reliable measurement results in laboratory medicine.

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The potential of single cells

The future of health diagnostics begins at the level of the individual cell

The cell is the basic unit of our body – and key to understanding the biology of good health, as well as how molecular dysfunction leads to disease. Yet our understanding of the hundreds of cell types and subtypes in the human body is still very limited and often based on techniques with ...

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The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.

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