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Weighing in the US Pharmacopeia

Minimum Weight and Routine Testing According General Chapters 41 and 1251

Weighing is one of the key activities carried out in every QC laboratory. Usually, it is one of the first parts of a whole analysis chain. As any weighing errors have the potential to propagate through the whole analysis and deliver an inaccurate final result, the United States Pharmacopeia (USP) ...

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Surprisingly simple molecules as potential OLED-Emitters?

Improving the efficiency of organic light emitting diodes with aromatic carbonyls

Organic light emitting diodes (OLEDs) are presently conquering the market for displays of smartphones and TVs. They also have a great potential in lighting applications. Current devices for the blue part of the visible spectrum lag behind their green and red counterparts in terms of efficiency ...

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Assessing the lung toxicity of air pollutants

Automated exposure of human lung cells at the air-liquid interface

The current debates on driving bans in European cities show not only how important air quality is to the public but also reveal the lack of available methods to directly assess the adverse effects of air pollutants on human health.

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Light plus current: The formula for researching what happens to individual nanoparticles

Electrochemical dark-field microscopy can visualize and help investigate the reactions of individual nanoparticles

A combination of dark-field microscopy and electrochemistry can make individual nanoparticles in a liquid medium visible. The technique is suited to determine the activity of catalysts during their use.

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“Game over” for the Paris kilogram

The new definition of the SI base unit of mass and its significance to the weighing world

For about 200 years, any mass given in kilograms, grams and micrograms referred to a defined artifact accessible in only a single location on earth. A small metal cylinder had represented one kilogram since the metric system was introduced in France. Its successor became world famous as the ...

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Natural constants take center stage

A fundamental change in the International System of Units

The 20th of May 2019 is a special day. From that day on, the old definitions of what a kilogram, a mole, an ampere and a kelvin represent, are history. The future of the International System of Units will see natural constants play the star roles.

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How the Avogadro constant was measured for the last time

Determining the basis for the redefinition of the units kilogram and mole

Since the 20th of May 2019, the mass unit kilogram is no longer defined by the international kilogram prototype but by the numerical value of the Planck constant, the most important fundamental constant in quantum physics. For this definition, the Planck constant needed to be measured with the ...

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From feast to famine and back – no problem for bacteria

Microorganisms use impressive strategies for dealing with uncertainty

Bacteria are true survivors. In the course of evolution, they have developed numerous strategies to adapt to rapidly changing, uncertain environmental conditions. Their metabolism is much more sophisticated than that of human beings. Within minutes they can regulate their gene expression and, if ...

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Infrared visualization of sucrose in plants

A novel microspectroscopic method allows sugar mapping across the plant tissue

Quantitative mapping of metabolite distribution has widespread applications in medicine and biology, but has remained a key analytical challenge. A novel method for sugar imag-ing in plants based on the principles of infrared spectroscopy, which was developed at the IPK-Gatersleben, allows the ...

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Lipidomics – a new kid on the “OMICS” block

An emerging technology to comprehensively describe entire lipid profiles

Progress in research is – to a large extent – driven by technological and analytical advance-ments. This is particularly true for the field of lipid research in the biomedical field, which was hampered for decades by the limited availability of analytical tools to address the enormous complexity ...

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