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156 q&more articles
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Using deep learning to better understand blood disorders
AI-based methods for classifying individual blood cells
For a long time, doctors have been diagnosing disorders of the body’s hematopoietic system using a light microscope. The analysis of individual blood cells is largely performed manually. Now, artificial intelligence can lend them a digital hand.
Chlorogenic acids in coffee
Analytics and multivariate data analysis of coffee phenols
Chlorogenic acids (CGAs) are, by definition, esters formed from hydroxycinnamic acids and quinic acid. As such, they are produced by almost all plant species as secondary metabolites. In our diet, we take up substantial amounts of this class of compounds – around 1 g per day, in extreme cases ...
3D tissue models with immune competence
Immune-responsive human tissue models for the development of immunomodulatory drugs
Innate immunity is a central component of the human immune defense. Pattern recognition receptors (PRRs), such as the toll-like receptors (TLRs), play a key role in this system. They are omnipresent in nature and found in plants, insects, vertebrates and human beings.
A fast route to automated powerful data
Deep learning and convolutional neural networks in microscopy
The advent of accessible, easy-to-use high-content screening systems has brought many benefits to life science. However, this increased access to large amounts of images also brings challenges, for example relating to data processing, statistical analysis and automation. Addressing these ...
Securing data jewels within the data lake
Data governance as a strategy for value-added data and digitalization in the laboratory
In the field of data analytics and machine learning, data quality and the “right” data architectures are the key to success. Data governance enables organizations to establish important elements and processes for generating value-added information from data.
Customized ligands pave the way for new reaction pathways
A catalyst with high selectivity for converting organolithium compounds
For the first time, an efficient catalyst for palladium-catalyzed C–C bonding between aryl chlorides and alkyl lithium compounds has been found. This reaction enables simpler synthesis routes for important products, such as pharmaceuticals, while avoiding much salt waste.
Synthetic receptors for viruses
Surface-imprinted hybrid materials for the selective detection of viruses
Thanks to technological advances in polymer chemistry and nanotechnology, it is now possible to synthetically produce nanomaterials with a wide range of properties and functionalities. This has paved the way for producing bio-inspired structures and systems which, for example, possess binding ...
The traceability of measurement results
Metrological traceability: central concept of metrology and requirement of accreditation standards worldwide
Metrological traceability is necessary for consistent, comparable and valid measurement values. As a fundamental concept of modern-day metrology, it allows measurement results to be internationally recognized and is required by norms and accreditation standards all over the world. The ...
On the way to the cyber-physical lab
Requirements for smart laboratory instruments and interconnected systems in the modular lab of the future
Laboratories tend to be central hubs for chemical, biotechnological, pharmaceutical or foodstuff production. They play a key role in research and development, chemical analysis, quality assurance, maintenance and process control.
How gold plasma can make hidden structures visible
Chryso-CT adds contrast to surfaces in X-ray computed tomography
In recent years, microcomputed tomography (μCT) has become a standard method in many medical, scientific and industrial fields. This non-invasive technique enables three-dimensional imaging of a wide variety of structures. However, a new combination of methods now makes it possible to visualize ...
q&more – the networking platform for quality excellence in lab and process
The q&more concept is to increase the visibility of recent research and innovative solutions, and support the exchange of knowledge. In the broad spectrum of subjects covered, the focus is on achieving maximum quality in highly innovative sectors. As a modern knowledge platform, q&more offers market participants one-of-a-kind networking opportunities. Cutting-edge research is presented by authors of international repute. Attractively presented in a high-quality context, and published in German and English, the original articles introduce new concepts and highlight unconventional solution strategies.
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