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6 q&more articles about the topic active ingredientsrss
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Research at the interface between fundamentals and application
Medical progress is facing a crisis: the significant investments into the development of new therapies in recent years have not resulted in an increase in approvals of innovative drugs. The number of newly launched medications has already been stagnating for some time, although pharmaceutical ...
More efficient drug design through the understanding of experimental uncertainty
Biology is naturally complex, and even the results of the simplest biochemical experiments are afflicted with experimental noise that cannot be ignored. However, biochemical measurements are the backbone of modern pharmaceutical research. If the experimental uncertainty is underestimated, ...
Quality in pharmaceutical manufacturing – validation is more than only testing
Biotechnological medicinal products offer great opportunities for up to now incurable diseases. Hence, they represent nowadays a significant and growing market. Nevertheless their heterogeneity still remain a big challenge. A major challenge with biopharmaceuticals is their heterogeneity. In ...
Efficient synthesis of an anti-malarial agent in a continuous-flow microreactor
Malaria represents a global threat to health, which is difficult to keep under control. Amongst more than 200 million sufferers, over 500,000 die each year of the disease, with the risk of a fatal outcome being particularly high in children .
Safe handling of highly potent active ingredients in chemistry
New drugs are developed, among other reasons, with the aim of reducing dosage and having more targeted active ingredients. For patients, this development is definitely beneficial. These ingredients are described as highly potent active ingredients. But what does highly potent mean? And how are ...
Bacterial surface display for the identification of active ingredients for the pharmaceutical and cosmetics industry
Coupling biological molecules to surfaces, and using them in this form for measurement procedures, for analysis and in production processes, is a novel approach that is gaining increasing importance in industrial applications. Using established procedures, surfaces and biological molecules are ...
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