On the 125th death anniversary of Carl Remigius Fresenius (1818–1897)

The chemist Carl Remigius Fresenius died on June 11th, 1897. Among his students were Edward and Otto Mallinckrodt, sons of the founder of the company Mallinckrodt in the United States, which is still successful today. In a commemorative publication on the company’s 125th anniversary in 1992, it ...

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Analytics and multivariate data analysis of coffee phenols

Chlorogenic acids (CGAs) are, by definition, esters formed from hydroxycinnamic acids and quinic acid. As such, they are produced by almost all plant species as secondary metabolites. In our diet, we take up substantial amounts of this class of compounds – around 1 g per day, in extreme cases ...

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Carl Remigius Fresenius (1818–1897), a pioneer of analytical chemistry

On December 28, 2018, Carl Remigius Fresenius would have celebrated his 200th birthday (Fig. 1.) Not only was he a scientist but also an innovative entrepreneur as well as the teacher of about 5,000 students during the more than fifty years of his pioneering, enduring professional work. It is ...

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Multi-elemental analysis of diatoms using single-cell-ICP-TOF-MS

In today’s laboratories, elemental analysis methods are used for more than just determining total metal content in various sample matrices. They have become an important tool for life science research in environmental science, medicine and biology.

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A comparison of different analysis techniques for determination and species analysis of mercury

Mercury is undisputedly one of the most toxic elements. In 2013, the Minamata Convention on Mer-cury to restrict the production and emission of this heavy metal was adopted in Geneva. It regulates the production, use and storage of mercury. For example, new mines may no longer be built and ...

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Using photoionization mass spectrometry for online analysis and control of the coffee roasting process

Turning green coffee into roasted brown beans conjures myths, trends and desires. From the small gourmet roaster to the industrial plant, the growing consumer interest in quality and variety has increased the need to understand and influence the processes that take place when coffee is being ...

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Discovering compounds that matter for food safety along the global food chain

More than ever, consumers are concerned about the food they consume. For example, for botanical extracts used in food products and food supplements, fraud is quite common. It is evident that specifications, quality control and regulation of botanicals need to be improved [1-3].

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Minimum Weight and Routine Testing According General Chapters 41 and 1251

Weighing is one of the key activities carried out in every QC laboratory. Usually, it is one of the first parts of a whole analysis chain. As any weighing errors have the potential to propagate through the whole analysis and deliver an inaccurate final result, the United States Pharmacopeia (USP) ...

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Generating aptamers using an automated in vitro selection method

DNA and RNA aptamers are high-affinity, nucleotide-based binding molecules which, as an alternative to antibodies, are already being widely used in analytics, diagnostics and therapeutics. The generation of new aptamers and their industrial implementation opens up new potentials for a wide range ...

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Why a single analysis parameter is not enough

Authentic food is growing in popularity with consumers. In a heavily industrialized market, a regional, single-source and/or specially manufactured product is increasingly becoming a guarantor of greater value. In the premium segment in particular, economically motivated “food fraud” can reap ...

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