Minimum Weight and Routine Testing According General Chapters 41 and 1251

Weighing is one of the key activities carried out in every QC laboratory. Usually, it is one of the first parts of a whole analysis chain. As any weighing errors have the potential to propagate through the whole analysis and deliver an inaccurate final result, the United States Pharmacopeia (USP) ...

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The new definition of the SI base unit of mass and its significance to the weighing world

For about 200 years, any mass given in kilograms, grams and micrograms referred to a defined artifact accessible in only a single location on earth. A small metal cylinder had represented one kilogram since the metric system was introduced in France. Its successor became world famous as the ...

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Superconducting levitation enables ultra-clean sterile processes

Like counting objects, measuring their mass belongs to the most elemental characterization processes mankind has performed for thousands of years, from coal bags to sophisticated agents used in the pharma industry, from beam balances to electromagnetic laboratory balances, and from micro to kilo ...

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First-Defect-Stop helps to improve quality through sustainable and reliable processes in weighing

The management concept “Lean Laboratory” is increasingly being implemented in the laboratory environment, with the aim of optimizing efficiency. An essential approach here is the “First-Defect-Stop”, which is based on the Jidoka principle and refers to the earliest possible identification of ...

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The new world of automated dosing

Every scientist studying at university was confronted in chemical practicals with the problem of dissolving a given powdered substance in a given solution and producing a solution with the prescribed ­concentration. The first step was to weigh. Armed with a spatula and a small sheet of weighing ...

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GWP® (Good Weighing Practice™) Life Cycle Management – 5 steps that support the Lean principles perfectly

A Lean Laboratory focuses on testing products and materials to deliver results in the most efficient way in terms of cost and speed. An accurate result for the customer is a pre-requisite. However, to guarantee accuracy of a weighing device over time requires using the correct balance as well as ...

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Powerfull solutions for the future

The international growth markets of the chemical and pharmaceutical industries, particularly in the life sciences area, are characterised by strong dynamics. Interdisciplinary collaboration between various scientific disciplines and technologies is becoming increasingly important and produces a ...

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Gravimetric solutions for pipette calibration

Regular testing is essential to ensure that pipettes work accurately and precisely. However, measuring the volume of liquids is subject to inherent risks, particularly when the volume is small. Gravimetric solutions for testing and calibrating pipettes offer precise and regulatory compliant ...

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Improving the Efficiency and Quality of Analytical Workflows

Analytical sample and standard preparation in a pharmaceutical or QA/QC laboratory is typically a manual procedure that requires that solids be weighed and diluted to the mark volumetrically. A minimum of 50 ml of solution is usually prepared for analytical measurements, even though the amount ...

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U.S. Pharmacopeia Convention (USP) defines changes to balances testing procedures

The U.S. Pharmacopoeia Convention (USP) has recently published a revised version of its mandatory chapter 41 (Balances) plus amendments to chapter 1251 (Weighing on an Analytical Balance). Effective 1 December 2013, the revised chapters mean pharmaceutical companies are now facing the problem of ...

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