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22 q&more articles about the topic chemistry

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Highly-prized components

Rapid, gentle extraction of plant-derived ingredients for concentration in plant oils

The isolation of bioactive plant ingredients, essential oils or dyes and flavourings of plant origin requires costly and sophisticated procedures. Several applications do not actually require isolation of the individual components, however – their concentration is sufficient. Moreover, for ...

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Detecting and manipulating ions

From Potentiometry to the Nanoscale

The pH electrode is now ubiquitous for the monitoring of chemical processes. Progress in materials chemistry and fundamental methodology opens the door to new exciting approaches.

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Towards nanomedicine

Assets of hydrogenated detonation nanodiamonds for biomedical applications

Diamond nanoparticles or nanodiamonds (NDs) behave several essential assets for biomedical applications: their very weak cytotoxicity and genotoxicity [1], their carbon-related surface chemistry for covalent functionalization of targeting or labeling moieties (oligonucleotides, proteins, ...

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Bridging the Valley of Death

The emerging imperative of Translational Science in the development of new drugs

Most managers of pharmaceutical R&D define “translational science” as the translation of science to clinical practice by using novel means of analysis, allowing one to make inferences about the performance of a drug candidate much earlier than traditionally organized research would allow.

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Challenges

Interview with Dr. Jennifer L. Young, ACS Green Chemistry Institute®, American Chemical Society

Green Chemistry is one of the leading topics in the market today – sustainability gains more and more in importance for the strategic development of companies. The term „Green Chemistry“ was coined in 1991 ­and aims for the protection of human health and the environment. Twelve principles of ...

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With Light in the Fight against Malaria

Efficient synthesis of an anti-malarial agent in a continuous-flow microreactor

Malaria represents a global threat to health, which is difficult to keep under control. Amongst more than 200 million sufferers, over 500,000 die each year of the disease, with the risk of a fatal outcome being particularly high in children [1].

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The Beginning of the End?

Or The End of the Beginning?

Those of us who have been either directly involved in, or on the periphery of, the pharmaceutical industry over the last decade have seen at first hand a dramatic change. Times change, and technology changes. Take computer data storage for example. Not so long ago, the floppy disk was state of ...

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Interesting Health Promoters

The in vivo-metabolism of flavonoids: a challenge for analytics and pharmacology

There is barely a class of compounds among the secondary metabolites of plants that is so prominently represented in our lives as that of the flavonoids. They are found in ­numerous food substances in various oxidation states, and principally as glycosides (Fig. 1). By consuming fruit, vegetables ...

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DIN/ISO Compliant Calibrations

Essential performance characteristics in instrumental analysis

Today Analytical Chemistry is embedded in a strictly regulated environment and it has to be ensured that verifiable and officially authorised methods are used. How can this be achieved in a reproducible and unequivocal way? Here we approach this question with respect to the problem of ...

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Perfect Coordination

Safe handling of highly potent active ingredients in chemistry

New drugs are developed, among other reasons, with the aim of reducing dosage and having more targeted active ingredients. For patients, this development is definitely beneficial. These ingredients are described as highly potent active ingredients. But what does highly potent mean? And how are ...

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