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8 q&more articles about the topic sample preparation

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HPLC with non-specific detection in pharmaceutical quality control

Smart sample preparation improves selectivity of analytical procedures for biopharmaceuticals and other drug products

Impurity testing is an essential part of pharmaceutical quality control because toxicity and content of impurities contained in drug products can impair patient safety. This requires suitable, validated analytical methods.

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Detect and solve process problems immediately with Jidoka

First-Defect-Stop helps to improve quality through sustainable and reliable processes in weighing

The management concept “Lean Laboratory” is increasingly being implemented in the laboratory environment, with the aim of optimizing efficiency. An essential approach here is the “First-Defect-Stop”, which is based on the Jidoka principle and refers to the earliest possible identification of ...

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“Work smarter, not harder”

Lean methods come to the lab…at last!

Is “lean lab“ just a management trend du jour or something which you need to carefully consider? The successful introduction of lean manufacturing into industrial production was completed years ago and is now an indispensable part of today’s highly competitive markets.

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Safe food

Testing institute benefits greatly from automated sample preparation

German test laboratory Labor Friedle GmbH analyses food and food ingredient samples. Throughput and traceability are essential for providing an efficient and professional service to its customers.

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A turning point

Where does manual sample preparation stand?

The pressure is on to do more with less. Whether this applies to increased workload with lower headcount or more analytical tests with less milligrams of sample, how can today’s pharmaceutical and biopharmaceutical companies make ends meet?

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A Complex Mixture

Automated MOSH/MOAH determination with the aid of coupled LC-GC

Once only of academic interest, the combination of liquid chromatographic separation with subsequent separation in the gas-phase is proving to be suitable for routine use. In routine laboratory work, the method continues to present a major challenge, above all with regard to precision, ...

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The Benefits of Gravimetric Sample Preparation

Improving the Efficiency and Quality of Analytical Workflows

Analytical sample and standard preparation in a pharmaceutical or QA/QC laboratory is typically a manual procedure that requires that solids be weighed and diluted to the mark volumetrically. A minimum of 50 ml of solution is usually prepared for analytical measurements, even though the amount ...

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Keeping the Workflow in Focus

Practical implementation of a gravimetric approach to sample preparation

There has been much discussion surrounding the benefits of gravimetric sample preparation during the last 12 months . It has been recognised by industry organisations such as the United States Pharmacopeia (USP) who proposed an update to sub-chapter “Weighing on an Analytical Balance” in ...

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